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Editors-in-Chief: CG Sun PhD, Prof.
ISSN 2538-130X
4TMR Theory and Hypothesis is a peer-reviewed quarterly journal sponsored by TMR publishing group. It has been included in ScienceOpen and Google Scholar. The journal primarily aims to include innovative papers that combine these two theories with modern biomedicine, physics, chemistry and mathematic models. Hypotheses, basic and clinical researches, literature review and analysis which are carried out on a certain theory, phenomenon and development process of traditional Chinese medicine, and paper that reported the influence of traditional medicine on politics, economy, and culture can also be included. ... More


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Current Issue     20 December 2019, Volume 2 Issue 4 Previous Issue   
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Application value of tongue coating microflora in integration of traditional Chinese medicine and modern medicine
Juan Wu, Jun Qian, Li-Yun Shi, Zhen Zhan, Jun-Feng Zhang
4TMR Theory and Hypothesis. 2019, 2 (4): 229-240.   https://doi.org/10.12032/TMRTH201904001
Abstract ( 40 )     PDF (393KB) ( 19 )  
Observation of tongue coating is the characteristic content of traditional Chinese medicine syndrome differentiation and treatment. The microflora is the important component of tongue coating besides the desquamated epithelial cells. Tongue coating microflora might be an important linkage between the modern medical research and the classic traditional Chinese medicine theory. Therefore, the present paper summarised the application value of tongue coating microflora in health and disease to enrich the scientific connotation of traditional Chinese medicine tongue diagnosis and promote the development of integration of traditional Chinese medicine and modern medicine.
Potential new metabolic approach for treatment of diabetes mellitus: converting glucose to ascorbic acid (vitamin C)
Payam Hashemi, Shaghayegh Pezeshki
4TMR Theory and Hypothesis. 2019, 2 (4): 241-248.   https://doi.org/10.12032/TMRTH201904002
Abstract ( 71 )     PDF (428KB) ( 47 )  
Through changing in lifestyle and increasing the global prevalence of diabetes mellitus, its crucial to find new approaches for treatment of this disease. This metabolic disease is characterized by hyperglycemia, insulin deficiency or insulin resistance. This disorder categorized into type 1 and type 2 diabetes. Type 1 usually initiate from childhood, have an autoimmune background and associated with destroying of beta cells of pancreas. Type 2 diabetes is defined as insulin resistance, hyperglycemia and usually appears in adulthood. In the process of diabetes, hyperglycemia and oxidative stress can induce diabetic retinopathy, nephropathy, neuropathy and cardiovascular disease. According to literature, oxidative stress and chronic inflammation play an essential role in initiation and development of the complications of diabetes. Hence, inhibition of chronic inflammation and oxidative stress besides with glycemic control is important to prevent from these clinical complications. Some researches explained the antioxidant and anti- inflammatory property of vitamin C in patients with diabetes mellitus. Moreover, ascorbic acid can help to better glycemic control in these patients. Thus, we propose a new idea to convert excess amount of glucose to vitamin C for treatment of patients with diabetes mellitus. By performing this idea, we can achieve to better clinical management of diabetes in terms of glycemic control and prevention of oxidative
stress which lead to significant decrease in clinical complications.
Medical ethics w.s.r to ayurveda
Dr preetam k Lamani
4TMR Theory and Hypothesis. 2019, 2 (4): 249-251.   https://doi.org/10.12032/TMRTH201904003
Abstract ( 25 )     PDF (255KB) ( 15 )  
With nearly 5,000,000 Indians dying due to medical negligence every year.there is a circular relationship between nature and humankind because human concepts are nature’s concepts. Human technological and economic inventiveness is no more than nature’s way of acting upon itself and shaping its own future. The outcome could be glorious success or disastrous failure - in either case, nature acting through humankind bears partial responsibility for the outcome. A basic knowledge of how judicial forums deal with the cases relating to medical negligence is of absolute necessity for doctors. The need for such knowledge is more now than before in light of higher premium being placed by the Indian forums on the value of human life and suffering, and perhaps rightly so. Judicial forums, while seeking to identify delinquents and delinquency in the cases of medical negligence, actually aim at striking a careful balance between the autonomy of a doctor to make judgments and the rights of a patient to be dealt with fairly.Agadatantra one among eight branches of ayurveda has given good references in regard to medcal ethics and also how to overcome the burden of medical negligence merely by identifying the treating doctor.
Analysis of uterine artery and sex hormones in treating diminished ovarian reserve with tiaojing decoction
Meng-Jie Wang, Hui-Jun Xu
4TMR Theory and Hypothesis. 2019, 2 (4): 252-259.   https://doi.org/10.12032/TMRTH201904004
Abstract ( 24 )     PDF (493KB) ( 13 )  
Objective: To observe the effect of tiaojing decoction and climen on diminished ovarian reserve patients with deficiency of Kidney-Yin by sex hormone and uterine artery blood flow parameters. To verify the effectiveness of tiaojing decoction on diminished ovarian reserve and uterine artery blood flow parameters, explore the correlation between uterine artery blood flow parameters and sex hormones. Methods: Total 60 diminished ovarian reserve patients with deficiency of Kidney-Yin were randomly divided into the experimental group (n=30, taking tiaojing decoction and climen) and the control group (n=30, taking climen) and they were treated in 3 months. Observe bFSH, bE2, uterine artery PSV, EDV, S/D, RI before and after the treatment in the 2-4 day of menstruation. Results: After treatment, serum sex hormone levels and uterine artery blood flow parameters of the two groups were significantly different (P < 0.05), and the experimental group was significantly better than the control group. There was a linear correlation between PSV and FSH, PSV and
E2, FSH and E2. Conclusion: Tiaojing decoction combined with climen has significant effect on diminished ovarian reserve patients with deficiency of Kidney-Yin. Uterine artery blood flow parameters can reflect the sex hormone levels.
Interpretation of data and treatment of Jing-well point temperatures´ test
Lei-Ming Wang, Kang Tan, Li-Hao Chen
4TMR Theory and Hypothesis. 2019, 2 (4): 260-266.   https://doi.org/10.12032/TMRTH201904005
Abstract ( 26 )     PDF (420KB) ( 18 )  
The Jing-well point temperatures´ test method is a method to diagnose and guide the treatment of diseases by measuring the subjects' symmetrical well point temperature. it is improved from the method of knowing heat sensitivity. The application of Jing-well point temperatures´ test method is wide, and it can be used in internal and external gynecology and pediatrics and facial features department. at the same time, it has the advantage of objective and accurate diagnosis. The old law has some shortcomings, such as poor intuition, unavoidable omission of information, incomplete interpretation of information and so on. In this paper, Excel software is used to transform the data into line chart form, which improves the intuition and comprehensiveness of this method, so that the data can be better interpreted and used. It is newly proposed in this article that in addition to observing the longitudinal difference of well point temperature, more attention should be paid to the horizontal contrast difference of well point temperature in different meridians. The article also summarizes a number of treatment methods, including acupuncture, moxa moxibustion, cupping and scraping, and the selection of acupoints, including mother acupoints, tenderness points and heat-sensitive moxibustion, so that doctors can combine traditional Chinese medicine professional knowledge in clinic.

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