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93TMR Cancer  2019, Vol. 2 Issue (4): 233-238    DOI: 10.12032/TMRC201800059
Integrative Oncology     
Miao medicine may serve as an essential adjuvant therapy in cancer treatment
Dong-Xue Sun1, Zhu Yang1, Feng-Xi Long1, Ming-Zhu Li1, Guo Chen1, Dong-Xin Tang1,2,*()
1Guizhou University of Traditional Chinese Medicine, Guiyang 550002, China.
2First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, NO.71 Baoshan North Road, Yuyan District, Guiyang 550001, China.
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Highlights

Miao medicine may serve as an adjuvant therapy in cancer treatment.

Miao medicine may reduce the recurrence and metastasis rate after tumor surgery.

Comments

Traditional Chinese medicine includes many kinds of regional ethnic medicine, such as Miao medicine. Miao medicine has unique insights in cancer treatment. Studies on Miao medicine is still insufficient, its unique treatment methods may bring new ideas to cancer treatment. The use of Miao medicine in treating cancer may require more experimental and clinical evidence

Abstract

The Miao people have formed a unique treatment method for diseases in the long-term survival and development process, which lead to the formation of Miao medicine. Miao medicine is a kind of regional ethnic medicine in traditional Chinese medicine. Many studies and clinical trials have proved that Miao medicine played an active role in the prevention, treatment, and rehabilitation of tumors, which may reduce the recurrence and metastasis rate after tumor surgery, and decrease the toxic and side effects caused by radiotherapy and chemotherapy. Furthermore, Miao medicine may improve immunity and prolong the overall survival of patients with tumor. All these indicate that Miao medicine may serve as an essential adjuvant therapy. This article describes the specific application of Miao medicine in clinical and provides a scientific basis of Miao medicine in the treatment of cancer.



Key wordsMiao medicine      Tumor      Combination therapy     
Received: 13 June 2019      Published: 20 September 2019
Corresponding Authors: Tang Dong-Xin   
E-mail: tangdongxin@sina.com
Cite this article:

Dong-Xue Sun, Zhu Yang, Feng-Xi Long, Ming-Zhu Li, Guo Chen, Dong-Xin Tang. Miao medicine may serve as an essential adjuvant therapy in cancer treatment. 93TMR Cancer, 2019, 2(4): 233-238. doi: 10.12032/TMRC201800059

URL:

https://www.tmrjournals.com/cancer/EN/10.12032/TMRC201800059     OR     https://www.tmrjournals.com/cancer/EN/Y2019/V2/I4/233

Name Mechanism
Tripterygium [30] Down-regulation of VEGFR-2, VEGF, COX-2, COX-1, MMP-9, TIE, et al.; inhibition of NF-κB, Akt signaling pathway
Panax ginseng [31] Regulation of HIF-1α, VEGF expression, inhibition of PI3K/Akt and ERK1/2 pathway
Scutellaria Baicalensis [32] Inhibition of VEGF, down-regulation of MMPs; inhibition of p53/Rb signaling pathway, down-regulation of LPSTLR4-TRAF6 pathway
Sophora [33] Down-regulation of MMP-9, MMP-2 expression, inhibition of NF-κB pathway
Asarum Sieboldii [34] Inhibition of HPV-DNA proliferation
Gekko [34] Inhibit tumor cell invasion and metastasis, up-regulate E-calpain, down-regulate Racl, VEGF expression level
Curcuma Longa [35] Inhibits VEGF and receptor expression, regulates NF-Kβ, Akt/mTOR signaling pathway
Whitmania [36] Inhibition of Ki-67 proliferating antigen and high expression of VEGF
Table 1 Anti-tumor neovascularization and related mechanisms of some Miao herbs
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