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7Drug Combination Therapy  2019, Vol. 1 Issue (3): 165-172    DOI: 10.12032/DCT201903004
Mini-Review     
A clue to potential therapeutic targets: application of integrative medicine and bioinformatics
Shi-Lin Xia1,2, Han Liu3, Shinobu Mizushima1, Akio Mizushima1*
1. Department of Palliative Medicine, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
2. Clinical Laboratory of Integrative Medicine, the First Affiliated Hospital of Dalian Medical University, Dalian, P.R.China.
3. Department of Oral Pathology, Dalian Medical University, Dalian, P.R. China.
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More and more evidence show that the targets of traditional Chinese medicine are a resource pool that contributes to the modern medicine. A key aspect of medicine research is to address the issue how to look for a clue of potential therapeutic molecular targets by interdisciplinary approaches. With the development of high throughput technology, a considerable amount of data has been emerging. The application of these big data is not so efficient as the generation of them. This paper attempts to show that interdisciplinary analysis contributes to the discovery of targets at the initial stage of drug research, indicating that it is necessary to explore the drug research and development with interdisciplinary approaches between integrative medicine and bioinformatics.



Key wordsIntegrative medicine      Bioinformatic analysis      Drug targets     
Received: 17 May 2019      Published: 08 August 2019
Fund:  
The study was supported by the grants from National Natural Science Foundation of China (No. 81703871), and Doctoral Start-up Foundation of Liaoning Province (No. 20170520408).
Corresponding Authors: Akio Mizushima, Department of Palliative Medicine, Graduate School of Medicine, Juntendo University, Tokyo, Japan.    
E-mail: akiom@juntendo.ac.jp.
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Shi-Lin Xia, Han Liu, Shinobu Mizushima, Akio Mizushima. A clue to potential therapeutic targets: application of integrative medicine and bioinformatics. 7Drug Combination Therapy, 2019, 1(3): 165-172. doi: 10.12032/DCT201903004

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https://www.tmrjournals.com/dct/EN/10.12032/DCT201903004     OR     https://www.tmrjournals.com/dct/EN/Y2019/V1/I3/165

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