Please wait a minute...
7Drug Combination Therapy  2019, Vol. 1 Issue (4): 237-244    DOI: 10.12032/DCT201904004
Review     
Research progress of Yinchenhao Decoction in the treatment of non-alcoholic fatty liver disease
Xiao-Ting Ma1, Jing-Na Zhou1, Shou-Jing Sheng1, Shao-Qin Ge1*
1. College of Traditional Chinese Medicine, Hebei University, Baoding, Hebei, 071000, China.
Download:   PDF(302KB)
Export: BibTeX | EndNote (RIS)      

Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide. Non-alcoholic steatohepatitis (NASH) is the most serious type and a turning point in the progression of NAFLD. If not treated actively, NASH will progress to irreversible liver damage such as cirrhosis and hepatocellular carcinoma. At present, there are no specific therapeutic drugs in western medicine. The treatment methods are mainly to improve lifestyle and exercise therapy, to alleviate the symptoms of discomfort, delay the progress of the disease, and improve the quality of life. However, the effect is often not ideal, prone to recurrence, and compliance is relatively poor. Dramatically, traditional Chinese medicine has certain advantages in the treatment of NAFLD. Modern research has confirmed that Yinchenhao Decoction has a good effect on liver-protective and choleretic action and improving liver function. It has significant curative effect on various liver and gallbladder diseases such as acute liver injury and alcoholic liver disease. This article summarized the clinical and basic research of Yinchenhao Decoction in the treatment of NAFLD. We found that Yinchenhao Decoction can enhance the efficiency of NAFLD and improve symptoms such as dizziness, liver pain, hepatosplenomegaly and indigestion. The mechanisms may be related to that Yinchenhao decoction improves the disorder of glucose and lipid metabolism, inflammatory state and liver function.


Key wordsYinchenhao Decoction      Non-alcoholic fatty liver disease      Non-alcoholic steatohepatitis     
Received: 04 July 2019      Published: 09 November 2019
Fund:  The study was funded by the Natural Science Foundation of Hebei Province (No. H2018201218).
Corresponding Authors: Shao-Qin Ge, College of Traditional Chinese Medicine, Hebei University, Baoding, Hebei, 071000, China.   
E-mail: gesq67@163.com.
Cite this article:

Xiao-Ting Ma, Jing-Na Zhou, Shou-Jing Sheng, Shao-Qin Ge. Research progress of Yinchenhao Decoction in the treatment of non-alcoholic fatty liver disease. 7Drug Combination Therapy, 2019, 1(4): 237-244. doi: 10.12032/DCT201904004

URL:

https://www.tmrjournals.com/dct/EN/10.12032/DCT201904004     OR     https://www.tmrjournals.com/dct/EN/Y2019/V1/I4/237

[1] Jin-Yu Zhang, Xian-Fa Cai . A network pharmacological study on the potential mechanism of Yinchenhao Decoction in treatment of chronic hepatitis B[J]. 7Drug Combination Therapy, 2019, 1(3): 134-152.