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8Food Therapy and Health Care  2019, Vol. 1 Issue (2): 56-62    DOI: 10.12032/FTHC201905005
Review     
Intestinal microflora in patients with liver disease
Man-Man Wu 1, Hai-Ning Yu1, Sheng-Rong Shen2*
1College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, China.
2Department of Food Science and Nutrition, Zhejiang University, Hangzhou, 310058, China
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Abstract  Intestinal microflora is closely related to the occurrence and development of liver diseases. The imbalance of intestinal microflora can cause the increase of endotoxin and change the metabolic pathways such as lipid metabolism, thus causing the occurrence of liver diseases. It is beneficial to explore the effects of intestinal microflora on metabolism and its relationship with liver disease, which maybe reveal the pathogenesis of liver disease and find new therapeutic targets for liver disease. This paper reviewed the effects of intestinal microflora on endotoxin, short-chain fatty acid metabolism, fatty acid metabolism, bile acid metabolism, choline metabolism and endogenous alcohol production, and analyzed the relationship between intestinal microflora and liver disease.

Key wordsIntestinal microflora      Liver disease      Intestinal microflora      Liver disease      Endotoxin      Metabolism     
Received: 11 January 2019      Published: 01 May 2019
Corresponding Authors: Sheng-Rong Shen, Department of Food Science and Nutrition, Zhejiang University, 310058 Hangzhou, China.      E-mail: shensr@hotmail.com
Cite this article:

Man-Man Wu, Hai-Ning Yu, Sheng-Rong Shen. Intestinal microflora in patients with liver disease. 8Food Therapy and Health Care, 2019, 1(2): 56-62.

URL:

https://www.tmrjournals.com/fthc/EN/10.12032/FTHC201905005     OR     https://www.tmrjournals.com/fthc/EN/Y2019/V1/I2/56

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