01 May 2020, Volume 2 Issue 2 Previous Issue   
Association of alcohol consumption with colorectal cancer risk: a dose-response meta-analysis
Yan Li, Zhi-Li Xu, Yi-Yi Cui, Yong Guo
8Food Therapy and Health Care. 2020, 2 (2): 40-53.   https://doi.org/10.12032/FTHC202005001
Abstract ( 88 )     PDF (1180KB) ( 70 )  

Background: Currently, there are many meta-analyses on the correlation between alcohol conception and the risk of colorectal cancer, but the findings are inconsistent. We conducted a dose-response meta-analysis to investigate the association between alcohol intake and the risk of colorectal cancer.

Methods: A literature search was performed on PubMed and EMBASE databases to identify relevant articles published before December 09, 2019. Summarized relative risks (RRs) and 95% confidence intervals (CIs) were calculated using a fixed or random-effects model for the dose-response meta-analysis. The Cochran Q and I2 statistics were used to assess statistical heterogeneity among studies.

Results: Five cohort and 19 case-control studies were included in the meta-analysis. An increased intake of 15-39.9g of daily alcohol was related to a 21% growth risk of CRC(RR=1.21, 95% CI: 1.05-1.38).Our dose-response analysis indicated that for drinkers of light, moderate and heavy level of alcohol drinking, the estimated RRs of CRC were 0.94( 95% CI: 0.69-1.27), 1.08( 95% CI: 0.93-1.26) and 1.90( 95% CI: 1.29-2.97) respectively and for drinkers of moderate beer, heavy beer, moderate wine and heavy wine intake, the estimated RRs of CRC were 0.98 (95% CI: 0.72-1.34), 1.48 (95% CI: 1.05-2.07), 0.86(95% CI: 0.56-1.34) and 1.04 (95% CI: 0.83-1.29) respectively. The risks with no significant association were consistent in the subgroup analyses of general alcohol consumption status and frequency.

Conclusions: Heavy level of alcohol consumption, especially heavy beer intake seems to be associated with an increased the risk of CRC.

Research progress on the relationship between exercise and tumor

Xuan-Ying Wang, Ning Lu
8Food Therapy and Health Care. 2020, 2 (2): 54-63.   https://doi.org/10.12032/FTHC202005002
Abstract ( 46 )     PDF (548KB) ( 54 )  

Tumor is a major threat of the health of Chinese people at present. Exercise has a certain relationship with tumor and is one of the hot topics in the research of tumor. In this paper, it made a review of the researches on the occurrence and development of tumor, therapeutic effect and prognosis, rehabilitation of tumor patients, and the effect of tumor on exercise in recent years. It indicates that the interaction between exercise and tumor is one of the best prevention methods for tumor and has a positive impact on the prognosis and rehabilitation of tumor patients. 

Orginal Article
Analysis of the rule of medication for internal administration of gout by traditional Chinese medicine based on Traditional Chinese Medicine Inheritance System
Yi-Hua Fan, Hong-Xia Xie, Ping Xin, Jin-Xiang Mao, Yu-Yan Zhang, Xin-Ju Li
8Food Therapy and Health Care. 2020, 2 (2): 64-78.   https://doi.org/10.12032/FTHC202005003
Abstract ( 178 )     PDF (673KB) ( 128 )  

Objective: Based on the TCMIS (traditional Chinese medicine inheritance system) V2.5 to explore the rule of medication used in internal TCM (traditional Chinese medicine) for gout in the national patent network. Method: Collect the internal administrations of gout in the national patent network, and enter them into the Chinese medicine inheritance system V2.5, adopt Frequency analysis, association rules, complex system entropy clustering and other data mining methods to analyse the internal traditional formula of traditional Chinese medicine for gout. Results: By inclusion, exclusion criteria, 357 formulas are screened out, involving 494 medicine, 63 medicine with frequency of use≥20, and 40 commonly used medicine pairs. The core medicine are: Huangbai (Cortex Phellodendri), Cangzhu (Rhizoma Atracylodis), Niuxi (Radix Acanthopanacis Bidentatae), Yiyiren (Semen Coicis), Tufuling (Rhizoma Smilacis Glabrae), Bixie (Rhizome Dioscoreae Hypoglaucae), Gancao (Radix Glycyrrhizae), Weilingxian (Radix Clematidis), Zexie (Rhizoma Alismatis), Danggui (Radix Angelicae Sinensis), Chuanxiong (Rhizoma Chuanxiong). There are 28 new combinations and 14 new formulas. Conclusion: In the national patent network, the internal traditional Chinese medicine for gout is based on clearing away heat and dampness, activating blood circulation to dredge collaterals, which provides reference for clinical treatment of gout.


Progress on antioxidant activity of single or compound traditional Chinese medicine

Teng-Fei Liu, Dan-Dan Xie, Li-Qin Jiang
8Food Therapy and Health Care. 2020, 2 (2): 79-85.   https://doi.org/10.12032/FTHC202005004
Abstract ( 48 )     PDF (301KB) ( 49 )  

Oxidative stress plays a key role in the pathogenesis of various diseases. Nature antioxidants derived from traditional Chinese medicine protect the cells and tissues from oxidative stress by scavenging free radicals and reactive oxygen species, therefore have a great potential in delaying ageing process and preventing oxidative stress-related disease. In this article, the antioxidant benefits of common single and compound traditional Chinese medicine in protecting tissues from injury are reviewed, along with identification of the various constituents that possess antioxidant activity and its mechanism were reviewed.

Research Progress on the Immunomodulatory Effect of Trace Element Selenium and Its Effect on Immune-Related Diseases

Yao Lin, Li-Qin Jiang
8Food Therapy and Health Care. 2020, 2 (2): 86-98.   https://doi.org/10.12032/FTHC202005005
Abstract ( 67 )     PDF (490KB) ( 50 )  

Selenium, one of the essential trace elements in the body, has a variety of biological functions including antioxidant activity, immunity enhancement and anti-tumor effect, and has the potential to be further developed into new drugs. In this paper, the research progress on the immunomodulatory effect of selenium and its mechanism and the effects of immune-related diseases in recent years were reviewed, and its future research and application were prospected. It is hoped to provide reference for further exploring the immune regulation effect and application of selenium.