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2TMR Integrative Medicine  2018, Vol. 2 Issue (4): 197-201     DOI: 10.12032/TMRIM201802035
Clinical Research     
Based on the process management of traditional Chinese medicine comprehensive intervention method on outcomes in patients with mild / moderate chronic obstructive pulmonary disease: study protocol for a practical randomized controlled trial
Ming Ren1,*(),Li-Ping Guo2,*(),Xiao Sun2,Yang Qiao2,Lei Chen3,Lei Zhang3,Yan Shao3,Xiang-Li Han3,Huai-Ying Ding3,Jian-Mei Zhao3
1Baokang Hospital of Tianjin University of TCM, Tianjin, China.
2Tianjin University of TCM, 88 Yuquan Street, Nankai District, Tianjin, China.
3Fourth Teaching Hospital of Tianjin University of TCM, 90 Hangzhou Street, Binhai District, Tianjin, China.
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Highlights:

The practical randomized controlled trial reveal that the COPD patients will be benefit from therapy with Traditional Chinese medicine treatment.

Abstract

Background: The prevalence, morbidity and mortality of chronic obstructive pulmonary disease (COPD) is very high, so it has become a public health problem. The early stage of COPD has been paid much attention before it develops severely. As well, traditional Chinese medicine has some advantages in relieving symptoms and reducing the incidence of COPD exacerbations. Methods: A practical randomized controlled trial will be designed to test the clinical effects of traditional Chinese medicine treatment according to syndrome differentiation. A total of 80 patients with mild / moderate COPD will participate in this study, 40 in the treatment group and 40 in the control group. On the basis of the lifestyle intervention, traditional Chinese medicine formula granules for treatment group and the placebo simulation of traditional Chinese medicine granules for control group. The exacerbation and the improvement of pulmonary function will be used as the primary outcome measures. The improvement of clinical symptoms and signs, the quality of life and Dyspnea will be used as the secondary outcomes measures. Conclusion: We assume that the COPD patients will be benefit from therapy with Traditional Chinese medicine treatment.



Key wordsChronic obstructive pulmonary disease      Traditional Chinese medicine      Practical randomized controlled clinical trial     
Published: 14 December 2018
Fund:  Funding: This study was supported by Health Development Planning Commission Project of Binhai District in Tianjin (NO.2016BWKZ001), Science and Technology Planning Project of Tianjin Province(NO.15ZXLCSY00020), Science and Technology Development Strategy Planning Project of Tianjin province(NO.17ZLZXZF00670), Youth science fund project (NO.81102731), the ministry of education innovation team development plan the prevention of cardiovascular diseases in TCM (No.IRT_16R54).
Corresponding Authors: Ren Ming,Guo Li-Ping     E-mail: renming2008@126.com.;lpgtjn@163.com.
Cite this article:

Ming Ren, Li-Ping Guo, Xiao Sun, Yang Qiao, Lei Chen, Lei Zhang, Yan Shao, Xiang-Li Han, Huai-Ying Ding, Jian-Mei Zhao. Based on the process management of traditional Chinese medicine comprehensive intervention method on outcomes in patients with mild / moderate chronic obstructive pulmonary disease: study protocol for a practical randomized controlled trial. 2TMR Integrative Medicine, 2018, 2 (4): 197-201.  

URL:

https://www.tmrjournals.com/im/EN/10.12032/TMRIM201802035     OR     https://www.tmrjournals.com/im/EN/Y2018/V2/I4/197

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doi: 10.1186/1472-6882-12-197 pmid: 3528455
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