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2TMR Integrative Medicine  2019, 3: e19022.       DOI: 10.12032/TMRIM201903022
TCM syndrome types and the related factors in 145 cases of renal cell carcinoma
Dong Wang1, Yu Gao2, Xiao-Yu Zhu3, Jia Zhang1, Xi-Xing Wang2*
1Shanxi Provincial Institute of Traditional Chinese Medicine, Taiyuan, 030012, China. 2Shanxi Provincial Hospital of Traditional Chinese Medicine, Taiyuan, 030012, China. 3China Academy of Chinese Medical Sciences, Beijing, 100000, China.
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Background: To analyze the distribution of traditional Chinese medicine (TCM) syndromes and the related factors in patients with renal cell carcinoma, and to provide further guidance for the relapse prevention and combination of traditional Chinese and Western medicine in postoperative renal cancer patients. Methods: A retrospective survey was conducted to establish a postoperative clinical symptom assessment scale for patients with renal cell carcinoma. The distribution of TCM syndromes in 145 patients with renal cell carcinoma was analyzed statistically. Multivariate logistic regression was used to analyze the correlation between different TCM syndromes and risk factors. Results: The postoperative TCM syndromes of patients with cell carcinoma were mainly spleen-kidney deficiency (38.6%), liver-kidney Yin deficiency (15.9%), spleen-kidney Yang deficiency (13.1%), and damp-heat pouring downward (9.7%). The incidence of severe spleen-kidney Qi deficiency syndrome and spleen- kidney Yang deficiency syndrome was statistically different from that of liver-kidney Yin deficiency syndrome (P < 0.05). The history of drinking and BMI ≥ 24 kg/m2 were risk factors for spleen-kidney Qi deficiency syndrome; the history of hypertension was a protective factor for liver-kidney Yin deficiency syndrome after renal cancer surgery; male was a protective factor for patients with renal cancer who had damp-heat pouring downward syndrome; smoking history and drinking history were risk factors for damp-heat pouring downward; age was a protective factor for spleen-kidney Yang deficiency after renal cancer surgery. Conclusion: This study found that spleen-kidney Qi deficiency syndrome, liver-kidney Yin deficiency syndrome, spleen-kidney Yang deficiency syndrome, dampness and heat injection syndrome were the common TCM syndrome types after renal cell carcinoma patients. There was a correlation between the TCM syndromes of renal cell carcinoma and the risk factors such as drinking history, overweight and obesity, smoking history and drinking history. The distribution of TCM syndromes and its correlation with risk factors in renal cell carcinoma patients after surgery can provide ideas for clinical treatment and prognosis.

Key wordsRenal cell carcinoma       TCM syndrome       Constitution       Risk factors       Correlation study     
Published: 24 November 2019
Fund:  This work was funded by Shanxi Province. Shanxi Science and Technology Department Natural Fund Project (GDME-2016021168).
Corresponding Authors: Xi-Xing Wang, Shanxi Provincial Hospital of Traditional Chinese Medicine, Taiyuan, 030012, China.    
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Dong Wang, Yu Gao, Xiao-Yu Zhu, Jia Zhang, Xi-Xing Wang. TCM syndrome types and the related factors in 145 cases of renal cell carcinoma. 2TMR Integrative Medicine, 2019, 3: e19022.  

URL:     OR 3/88888

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