Editors-in-Chief: L Xiong, PhD
ISSN 2521-3415
2TMR Integrative Medicine is a peer reviewed, open access, and serialization open access (SOA) journal. It is dedicated to report the research progress and discusses the idea and method in clinical efficacy, action mechanism and theoretical research on integrative medicine, including evidence research, integrative research, alternative research, holistic research modernization research and other researches on integrative medicine around the world. It set up basic research, clinical research, case reports, review and theoretical discussion. There are hot topics include pharmacology research, toxicology research, theoretical research, clinical research, meta analysis, etc. It seeks to promote international communication focusing on the latest developments, trends, experiences and achievements on integrative medicine. It has been included in DOAJ, ScienceOpen, China Science and Technology Journal Database (CSTJ), and Google Scholar. ... More

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Current Year     2020, Volume 4 Previous Year   
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Quantitative and qualitative comparison of neonatal screening plan for the identification of hypothyroid neonates between Nahavand and Kashmar cities in 2016–2017 (respectively in the west and east of Iran)
Maryam Soori, Sedigheh Soleymani, Samira Tabaei, Manoochehr Solgi
2TMR Integrative Medicine. 2020, 4: e20002.   https://doi.org/10.12032/TMRIM202004002
Abstract ( 1 )     PDF (487KB) ( 0 )  

Background: Congenital hypothyroidism is the result of a reduction in thyroid hormone production or a decrease in the activity of thyroid hormone receptors and is one of the most preventable causes of mental retardation, deafness, and heart problems in the world. This study aimed to compare the prevalence of congenital hypothyroidism between Nahavand in the west of Iran and Kashmar in the east of Iran during the years 2016–2017. Methods: This is a cross-sectional descriptive study on neonates born in April 2016 to March 2018 in two cities of Nahavand and Kashmar. A few drops of blood from a baby's heel in 3–5 birthdays on a special filter paper (S & S903) became blood samples from the pelvic floor were filtered and dried. The valuation of the samples was performed by the enzyme linked immunosorbent assay method by evaluating the thyroid stimulating hormone. Premature infants, underweight (less than 2,500 grams), a weight of over 4 kg, multiple births, or newborns requiring blood transfusions or any newborn needed to be retaken to the test after two weeks. Results: In the city of Nahavand, the incidence of neonatal hypothyroidism in the years 2016 and 2017 were 6.7 and 9.09 per 1,000 live births. And for the city of Kashmar, this number increased to 5.6 and 4.3 per 1,000 births in 2016 and 2017, respectively. The mean rate of participation in the screening program in the first 3–5 days of birth in Nahavand during two years was 2016 and 2017 to 78.7% and in Kashmar about 94%, which indicates the higher participation of Kashmar. In the city of Nahavand, 64.6% of cases of hypothyroidism reported in boys' neonates and 51.5% of male children in the Kashmar city. Conclusion: The results of our survey indicates that the prevalence of hypothyroidism is high in both Kashmar in eastern Iran and Nahavand in western Iran. Especially in Nahavand city of western Iran, where the prevalence of hypothyroidism is higher than global and internal statistics. Further surveys are required to elucidate the role of iodine deficiency and family marriage in the hereafter.

Application of external treatment of traditional Chinese medicine in the treatment of cancer-related fatigue
Ting Yu, Jin-Lin Wu, Jia Wang, Dong-Xin Tang
2TMR Integrative Medicine. 2020, 4: e20001.   https://doi.org/10.12032/TMRIM202004001
Abstract ( 7 )     PDF (358KB) ( 13 )  

External treatment of traditional Chinese medicine (TCM), also known as external treatment of internal diseases, has many advantages, such as simple, easy to operate, cost-effective and so on. Therefore, external treatment of TCM is favored by the majority of medical workers. By consulting the domestic literature reports on the treatment of cancer-related fatigue (CRF), it is found that the external treatment of TCM has a significant effect on the intervention of CRF, and has a good effect on reducing fatigue, improving the quality of life and prolonging the survival time. The purpose of this paper is to summarize the application of several external treatments in this disease, and to provide a variety of references for clinical treatment of CRF.

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