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90Life Research  2019, Vol. 2 Issue (4): 145-151    DOI: 10.12032/life2019-1025-301
Review     
Research progress of the relationship between microvesicles derived from stem cells and nervous system diseases
Jiaping Yan1, Fuhao Qiao1,*()
1Department of Clinical Laboratory, Xintai Hospital of Traditional Chinese Medicine, Taian 271200, China
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Abstract  

Microvesicles, also called microparticles, are membranous vesicles released from the cell membrane surface or by exocytose. Almost any type of cells can secrete vesicles, especially stem cells. Recent years, stem cells are becoming a research hotspot of cytotherapy for their capacity of self-renewing, expansion and proliferation in vitro and the microvesicles derived from the conditioned medium of stem cells have been widely used to regenerative medicine because they are safer, easily obtained, measurable and cause no obvious immune rejection. Stem cells derived microvesicles have been confirmed to be closely related to the progress and treatment of atherosclerosis, diabetes, inflammation and tumor. This review focuses on the new progress of stem cells derived microvesicles treating various nervous system diseases and its application in biological therapy and the behind molecule mechanisms.



Key wordsStem cells      Microvesicles      Nervous system diseases      Biological therapy     
Received: 05 October 2019      Published: 24 October 2019
Fund:  This work was supported by the Shandong Medical and Health Technology Development Plan (2018WS047);Tai'an Science and Technology Development Plan (2017NS0246).
Corresponding Authors: Qiao Fuhao   
E-mail: qiaotingshanvip@163.com
Cite this article:

Jiaping Yan, Fuhao Qiao. Research progress of the relationship between microvesicles derived from stem cells and nervous system diseases. 90Life Research, 2019, 2(4): 145-151.

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https://www.tmrjournals.com/lr/EN/10.12032/life2019-1025-301     OR     https://www.tmrjournals.com/lr/EN/Y2019/V2/I4/145

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