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Efficacy of Qigong for the treatment of alopecia universalis:a clinical case report
Gómez Jensen Alberto Alejandro, Martínez Diana Elina, Wan Qing Guo
90Life Research    2019, 2 (1): 8-13.   https://doi.org/10.12032/life2019-0125-002
Abstract ( 617 HTML PDF (879KB) ( 127 )  

Qigong is a part of traditional Chinese medicine. According to the antique treaties, the foundations of traditional Chinese medicine are based in maintaining the harmony between Qi (energy), Jing (essence) and Shen (spirit). Alterations in this harmony can develop and determine the appearance of disease. Therapeutic effects of Qigong are helpful in the prevention and treatment of several diseases. It's main role in restoring body functions is due to the communication between internal organs, tissues and cells. The main goal of this work is to show the efficacy of Qigong in the treatment of a dermatological disease characterized by the appearance of circular or oval patches of missing hair, known as alopecia universalis. For western medicine the exact cause of this illness is not totally revealed, however, it's attributed to psycological, genetics and metabolic alterations. From the traditional Chinese medicine perspective, hair alterations are framed in the area of the water energy, represented by the kidney organ. The results of Qigong treatment suggested that the cranial hair follicles had been activated since the first treatment. As treatment progressed, the cranial hair follicles continued to grow, what's more, the brightness and pigmentation of the hair also increased. Therefore, in the clinical conditions evaluated, Qigong could be an effective alternative treatment in consideration of the visible evidence about rapid and long lasting results. Besides, we did not observe any side effects of Qigong in this case.

Young adults with depression—are we paying attention?—a review on depression in teenagers in the 21st Century
Shiruli Dash
90Life Research    2018, 1 (2): 32-39.   https://doi.org/10.12032/life2018-0811-001
Abstract ( 508 HTML PDF (1009KB) ( 177 )  

This review dives into the wide prevalence of depression among the adolescents of the current generation. The goal is to bring to light the interrelationship of factors that bring about depression and which, thus, must be the focus if more effective approaches to treating depression are to be established. The review forms the groundwork of depression, touching upon early history and progressing to prominent research studies that have been carried out across the globe. The role of drugs and peer pressure has been tied to the neurobiology of different regions of the brain and hormonal influences have simultaneously been studied. Questions have been raised and a critical analysis of the roots of depression has been made. Through an original interview conducted by the author with ten teenagers battling depression, the review highlights the universality of depression and the importance of acknowledging it and treating it in one of the most influential age groups today: the teenagers.

Depression and the ending of depression: tradition, science and subjectivities
Christopher Anthony David, Peter Gerard Coan
90Life Research    2018, 1 (2): 68-72.   https://doi.org/10.12032/life2018-0811-006
Abstract ( 440 HTML PDF (1648KB) ( 121 )  

What is depression? What causes it? How many people suffer from it? Why does it affect some people and not others? How can we test objectively whether a person is depressed or not? How can we best help depressed people? In this brief comment paper, we show that answers to these questions found in the current medical research literature are far from conclusive. We also point to existing research on alternative and complementary approaches to these questions, and call for more research in all these areas, especially incorporating ideas from Asian traditional medicine and religious traditions. Many successful approaches to the treatment of depression have originated outside the scientific community, and high quality unbiased research investigating the effectiveness of such methods has a significant contribution to make to scientific knowledge in this area.

Meta-analysis of NKX 2-5 polymorphisms on the risk of cardiovascular disease
Bo Liang, Mengting Jing, Huiling Liao
90Life Research    2018, 1 (2): 57-67.   https://doi.org/10.12032/life2018-1025-005
Abstract ( 421 HTML PDF (2559KB) ( 125 )  

Cardiovascular disease (CVD) remains the leading global cause of the death. Genetic polymorphisms in NKX 2-5 are found to be associated with CVD. However, the results were inconsistent and inconclusive. The present study performed a meta-analysis to get a more precise and comprehensive estimation of the association between the genetic polymorphisms in NKX 2-5 and the risk of CVD. The databases Pubmed, Chinese National Knowledge Infrastructure (CNKI), Wanfang Data and CQVIP were searched for related studies. A total of 9 studies including 1516 cases and 1438 controls were identified for the meta-analysis. The results indicate that the genetic polymorphisms in NKX 2-5 were associated with the significantly risks of CVD in the allelic model, dominant model, codominant model and superdominant model of rs3729753 (OR = 1.94, 2.00, 2.00 and 0.50 respectively) and rs118026695 (OR = 1.83, 1.98, 2.02 and 0.49 respectively). No significant associations were found between rs2277923 and g.1467G > A and CVD susceptibility in any of the studies. Therefore, rs3729753 and rs118026695 might be recommended as a predictor for the risk of CVD, while rs2277923 and g.1467G > A are not.

A darkfield microscopic evaluation of the live blood effects caused by Moringa oleifera
Howard W. Fisher, Colombe Gauvin
90Life Research    2019, 2 (3): 87-92.   https://doi.org/10.12032/life2019-0725-002
Abstract ( 418 HTML PDF (5462KB) ( 73 )  

Erythrocyte aggregation is the tendency of erythrocytes to form aggregates whose shapes change according to normal variations or pathological conditions. Consequently, regardless of cause, these anomalies effect changes to flow dynamics and predispose the inability to carry out transportation activities and decrease functional capillary density or decrease erythrocyte surface area, also decreasing functional efficiency. Functional capillary density is the determination of the number of capillaries in an area that have erythrocyte flow and relates to the subsequent ability of the blood to deliver nutrients, fluid and solute exchange, and waste product excretion. Red blood cell aggregation has a significant impact on functional capillary density. Moringa oleifera, one of the most phytonutrient dense plants as identified by the NIH, has garnered interest by those involved with anti-aging medicine. The US National Institutes of Health, the nation’s medical research agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce the burdens of illness and disability, has affirmed Moringa oleifera can “arrest, reverse, and cure, over 300 different diseases and disorders.” Regular use of Moringa oleifera has been shown to have a multitude of health benefits. In addition to this, Moringa oleifera provides all of the essential amino acids, vital vitamins, contains several important minerals, is an incredibly powerful antioxidant, is high in fiber, stimulates the immune system to fight cancerous cells, tumours, ulcers, epileptic seizures and cleanses and detoxifies the entire body. Moringa oleifera has been shown to protect platelets against aggregation. In this investigation, live blood microscopic evaluation indicates positive changes in the shape and spatial orientation of the erythrocytes and decreased incidence of aggregation and rouleaux indicating improved functional capillary density. In conclusion, a proprietary formula of raw organic Moringa oleifera has empirically demonstrated subjective beneficial changes in patients who have supplemented with this formula.

The relationship between the gender difference of depression and the polymorphism of AC-cAMP-PKA-CREB
Xiaobin Meng, Bo Zhao
90Life Research    2018, 1 (2): 51-56.   https://doi.org/10.12032/life2018-0811-004
Abstract ( 414 HTML PDF (1071KB) ( 106 )  

According to the study, 5-HT mediated AC-cAMP-PKA-CREB is associated with the onset of depression. In recent years, many researchers have expounded the pathogenesis of depression from the perspective of genetic polymorphism. Depression incidence has obvious gender differences, but its mechanism is not clear. Is depression genetically determined? Or does it result from one or more pathological determinants pathological? Which one is more important? On the basis of previous studies, the 5-HT mediated AC-cAMP-PKA-CREB pathway on four protein (5-HT1AR, 5-HT2AR, BDNF, TrkB) whose gene polymorphism and expression may be the keys. Further, 5-HT mediated AC-cAMP-PKA-CREB signaling pathway may be related to Gender differences in depression, so their gene polymorphism variation may provide new ideas for the research on gender differences in depression.

The exploration of information therapy forautism and dementia
Kean Hin Ooi, Pei See Sew, Irma van Tuil
90Life Research    2019, 2 (1): 1-7.   https://doi.org/10.12032/life2019-0125-004
Abstract ( 405 HTML PDF (984KB) ( 148 )  

This article provides explanations to how distance external Qi therapy works by quoting various rigorously designed controlled experiments conducted at various parts of the world. It also introduces a new method of therapy, information therapy that relies on the entanglement of information carried by low hissing sound playback with mp3 player to entangle with the information of subjects exhibited by the facial photo with the whole system placed in a sealed carton. Preliminary results have shown huge potential for information therapy to be applied on neurological cases, particularly on autism and dementia.

Taijiquan's Enigma
C.P. Ong
90Life Research    2019, 2 (1): 31-44.   https://doi.org/10.12032/life2019-0125-007
Abstract ( 362 HTML PDF (1462KB) ( 116 )  

Taijiquan is a martial art of the highest order is culturally etched in the Chinese heritage and entrenched in wushu pulp fiction and kungfu movies. Therein lies the enigma. The gentle slow-motion practice cannot be more remote from the speed and power of combat. And adding to the mystique is the proposition that Taijiquan's kungfu prowess is not drawn from the physical strength of the musculature but from some "inner strength" or Neijin. This sacred belief was desecrated when a fighter thrashed a self-proclaimed Taijiquan grandmaster ignominiously in 10 seconds in an open match. Taijiquan was then derided as a bogus combat art. The incident shakes the foundation of Taijiquan and puts into questions many of its touted claims, which challenges the scientific quest of the art. The paper confronts the issue directly by studying the manifestation of Neijin in the framework of science to provide a scientific basis for the art. It transcribes the yin-yang metaphysics that regulates Taijiquan training in terms of the alignment of muscle actions to balance and to unify momentum, which develops the core strength of Neijin and the underlying life-force Qi energy. From this flows the kungfu marvels, which lie in the liveliness and agility of Neijin's response and in the force ensuing that is of the right vector values, all essential in the fluidity of combat application. The martial aspect of Taijiquan provides a concrete representation of Neijin, which gives an experiential insight into the multifaceted concept of Qi, and in turn a pathway to the exploration of Qi in physiology and thus in Qi energy medicine.

Research progress of physical activity among patients with coronary heart disease: a literature review
Tingting Liu, Yaqian Liu, Mengjie Lei, Lina Meng, Changde Jin
90Life Research    2018, 1 (2): 45-50.   https://doi.org/10.12032/life2018-0921-003
Abstract ( 355 HTML PDF (910KB) ( 145 )  

As early as 2000 years ago, Huangdineijing, a classic Traditional Chinese Medicine book, has recorded that the heart plays a leading role in the operation of all organs, and if the function of the heart is unnormal, then the organs of the subordinates cannot perform their duties, thus affecting the normal physiological function activities. It also pointed out that temperate physical activity could make the body's airflow smooth, qi and blood balanced, and visceral function active, which was conducive to the physical and mental health of the human body. In modern medicine, coronary heart disease is also one of the most common coronary disease which affects people's health. And physical activity is proved to be closely related to rehabilitation and prognosis of patients with coronary heart disease. Since physical activity is good for coronary heart disease, so what is the current level of physical activity in patients with coronary heart disease? And what is the causes of different levels of it? Here, we reviewed the measurement and influencing factors of physical activity for coronary heart disease patients. This literature provided a basis for medical personnels to develop personalized exercise program.

Effects of music therapy in depression and anxiety disorder
Ednaldo Antonio dos Santos, Esperanza Marchant Sanchez, Maria Angeles Niguez Ortiz, Maria Amparo Oliver Germes
90Life Research    2019, 2 (2): 64-70.   https://doi.org/10.12032/life2019-0425-003
Abstract ( 353 HTML PDF (1019KB) ( 89 )  

Mental disorders are considerate "the evil of the century" by renowned researchers, because a large part of the population in many countries is a diagnosticated, and currently affect youth and children. Among the numerous therapeutic interventions, the music therapy is a non-invasive approach. However, there are very few people who are professionally engaged in research and studies on the subject. Therefore, this article is a literature to talk about the benefits of music therapy sessions for people with stress, depression and anxiety disorders.

Is Taijiquan a martial art or a dance?
C.P. Ong
90Life Research    2019, 2 (1): 48-51.   https://doi.org/10.12032/life2019-0125-006
Abstract ( 302 HTML PDF (614KB) ( 96 )  

After Xiaodong Xu, a Mixed Martial Arts (MMA) fighter, summarily crushed Wei Lei, a self-proclaimed Taijiquan grandmaster, in 10 seconds, he mocked Taijiquan, as well as other traditional kungfu arts as mostly fake and ineff ective in combat. The humiliation of the defeat and the put-down of the traditional arts touched a raw nerve. The wushu community was thrown into a convulsion and the Chinese social media went viral. The cultural comfort of the sacred belief of kungfu's superiority was shaken at the very core. The furor raged on for days and so consumed the cyberspace that the Chinese authorities shut down the debate and deactivated Xu's Weibo account.


Traditional Chinese medicine five-tone therapy
Haoran Zhang
90Life Research    2019, 2 (2): 80-83.   https://doi.org/10.12032/life2019-0425-005
Abstract ( 298 HTML PDF (399KB) ( 62 )  

From the perspective of the application of medical value orientation music therapy, this paper summarized the ancient Chinese sound therapy, such as shaman music therapy and five-tone therapy. It also compared five-tone therapy with Tibetan Singing bowl music therapy. The ancient music therapy is a kind of medical means which is oriented to the treatment effect. At first, it was mainly based on the music medical behavior of Taoist, and then gradually evolved into the modern treatment application of folk pentatonic therapy. On the basis of inheritance and development of ancient traditional music treatment, contemporary medicine proposed a new individualized music treatment. Therefore, the theory of five-tone therapy has updated the research on traditional Chinese music treatment theory and system, and will provide reference for the establishment of accurate music treatment system in the future.

Revealing the unseen human energy-- scientific understanding of Qigong
Life Research Editorial Group
90Life Research    2019, 2 (1): 45-47.   https://doi.org/10.12032/life2019-0125-001
Abstract ( 278 HTML PDF (2439KB) ( 65 )  

According to the earliest historical book in China (Shangshu), during the reign of Emperor Yao more than 4,000 years ago, people in central plains suffered from diseases such as joint pain due to the bad weather. So, they created some unique movements to regulate and improve the bodily functions, such as stretching the body to dissipate heat, curling up the body to keep out the cold. A large number of records in ancient Chinese books showed that Qigong practice was quite popular in ancient times. In particular, the book "Huangdi Neijing" describes in detail the requirements of practicing Qigong and the effect that can make people live longer, which is also known as "Daoyin". In modern age, various types of Qigong are still very popular around the world, such as Taiji Quan (Tai Chi), Baduan Jin, Wuqin Xi, and Six-character Formula in China, Yoga in India, Heka in Egypt and so on.


Using Qi flow in Taiji effecting structural change in feetand reduced pain: a case report
Suzanne Newnham
90Life Research    2019, 2 (1): 14-21.   https://doi.org/10.12032/life2019-0125-003
Abstract ( 277 HTML PDF (2336KB) ( 61 )  

In the article, the author reports on a case study of chronic pain problems caused by her own foot deformity. The author began using Taiji, Chen style Chan Si Gong (Reeling Silk), and Zhan Zhuang (standing meditation) to relieve chronic pain since 1986. After more than two years of Qigong training, the structure of the author's foot changed from the previous deformity to normal foot shape. These changes enabled the author to walk normally and to be free from persistent chronic pain. The article discussed the methods of using Qi currents and other issues that need to be paid attention to when practicing Tai chi, such as how to adjust one's mental focus and maintain a state of relaxation to "mindful". Tai chi involves a number of internal "micro-adjusting" about how these techniques relax and strengthen muscles to reduce chronic pain. The report and discussion on the treatment principle of Qigong can provide new strategies for the treatment of chronic pain.

Application of social contradiction analysis in the conflict between physicians and patients
Jia Song
90Life Research    2018, 1 (2): 40-44.   https://doi.org/10.12032/life2018-0811-002
Abstract ( 250 HTML PDF (877KB) ( 58 )  

There have been more and more violent medical injuries in China. Many physicians are too busy facing the case to work. The contradiction between physicians and patients harmed the physical and mental health of medical personnel, interfered the normal medical order, and caused great harm to society. Now Chinese physicians are going to treat patients according to the law rather than the actual situation. How to ensure the safety of medical practitioners and ease the medical contradictions has become an urgent problem to be solved. In contrast, 20 years ago, when traditional Chinese medicine was dominant in China, few people had heard of physician-patient conflict. How they handle relationships in traditional Chinese medicine clinic? Whether it can provide new inspiration for modern medicine system? Therefore, we used social contradictions analysis to find the underlying causes of medical conflict and put forward some new strategies drawing on the experience of traditional Chinese medicine.

The polygenic risk in schizophrenia: assessing GWASs and evaluating Clozapine, ECT and other treatment modalities
Shiruli Dash
90Life Research    2019, 2 (1): 22-30.   https://doi.org/10.12032/life2019-0125-005
Abstract ( 182 HTML PDF (4657KB) ( 76 )  

Research shows that the mortality rate among people with schizophrenia is up to four times higher than that in the general population. The subsequent high comorbidities and societal cost of schizophrenia necessitate finding better, more effective treatments and strategies for prevention. One of the current obstacles are the complicated gene etiologies that are involved in the pathophysiology of schizophrenia. So far, an increasing number of clinical and experimental studies show links between schizophrenia treatment and genetic conditions. Here, we analyze the literature on schizophrenia genetics, with a particular focus on the brain, the mind and environmental insults. An overlap of schizophrenia with other psychotic disorders has also been taken into account with an attempt to find a parallel relationship between genetics and treatment. Finally, we summarize all the present-day treatment options for schizophrenia like clozapine and electroconvulsive therapy and also take into consideration the relatively unexplored role of traditional Chinese medicine.

The application of improvisational music therapy in autism
Ferdinando M. Suvini
90Life Research    2019, 2 (2): 52-58.   https://doi.org/10.12032/life2019-0425-001
Abstract ( 126 HTML PDF (376KB) ( 11 )  

This article presents the model of improvisational music therapy and its use with people with autism. Firstly, the author provides a brief definition of some theoretical ideas and the clinical characteristics of improvisational music therapy, a relatively new treatment which is becoming more wide-spread on a global level. Particular reference is made to the possibilities which music offers in the creation of relational experiences, and the role of time, rhythm and repetition as regulatory elements both in music and in intersubjective relationships. Following this, the efficacy of improvisational music therapy with people with autism is discussed, with regard to research in the field of neuroscience (specifically, the Mirror Neuron System) and the impact of a multimodal stimulus such as music making. The final section outlines the results of the international research project RCT TIME-A, in which improvisational music therapy was used with children with autism. The literature analysis shows that music therapy has significant effects and contributes to improvements in several aspects of the autistic disorder, such as autistic mannerisms, social awareness and social affect. We can consider these results as the beginning of a pathway towards validating improvisation music therapy as a treatment for children with autism.

Empirical six-dimensional framework for slowing and reversing ageing using modern science and ancient wisdom
Asoka Nimal Jinadasa
90Life Research    2019, 2 (3): 106-112.   https://doi.org/10.12032/life2019-0725-303
Abstract ( 122 HTML PDF (1398KB) ( 33 )  

There are numerous published theories that cover the different biological processes relating to ageing. No one seems to have integrated such complex and seemingly unrelated information into a holistic framework that explains in simple terms the key aspects of ageing and provides a set of daily practices for staying young and healthy. An attempt is made here to select a 6-dimensional framework symbolized by heart, mind, passion, focus, body and health, and correlate it to the mental, emotional, physical and health aspects of ageing. Based on grounded theory, this paper empirically correlates 30 practical methods that can be used to develop all six dimensions, with 18 key factors that were found to influence ageing: Neurogenesis; Epigenetic reprogramming; Removing dying cells; Mitochondria resuscitation; Calorie restriction; Plant-based diet; Regular physical activity; Chi Kung (Qigong); Overcoming anxiety, depression and stress; Positive mind-set; Some worrying; Vitamins and minerals; L-Theanine; Omega-3 and healthy fats; Coenzyme Q-10; Pyrroloquinoline quinone; Nitric oxide; Choline. In this study, 26 references were used to establish that all 18 of these seemingly unrelated key anti-ageing factors can be developed using 30 daily practices derived from the 6-dimensional framework. These simple daily practices can help people of all ages to stay young and healthy, and help older people who are living alone to self-improve their quality of life without needing anyone to look after them. Since many anti-ageing drugs seem to be ineffective, this study provides a holistic new research direction for using modern science and ancient human energy practices combined with wholesome nutrition to slow ageing and age-related illnesses.

Exercise and nutrition research on longevity and quality life
Pierluigi Vagali
90Life Research    2019, 2 (3): 119-123.   https://doi.org/10.12032/life2019-0725-601
Abstract ( 119 HTML PDF (676KB) ( 35 )  

Exercise and Nutrition are complementary parts of a preventive and curative process to improve the quality of life, longevity and compress the life phase subject to disability. Physical activity and nutrition play an essential role both for the prevention of chronic non-communicable diseases and for their treatment. Nutraceuticals and exercise constitute the new frontier for healthy aging. We therefore motivate people by teaching them a new "life style", a delicate balance of adequate physical exercise and correct food hygiene, ensuring an unusual and surprising well-being and well-being, to which it will not be easier to give up.

Anti-aging theory of quantum nature and brain reprogramming
Yurii Pozniak
90Life Research    2019, 2 (3): 113-118.   https://doi.org/10.12032/life2019-0725-401
Abstract ( 117 HTML PDF (2093KB) ( 40 )  

As many scientists believe, human aging is a very important part of the program of life-human activity rather than a disease. The human brain may be the controller, performer and participant of the natural program of life-human activity, from birth to death. The program of life-activities of the brain and the human body is very similar to a conventional computer program and it may also be malfunctioning. The work of the natural program of life-activity resembles the work of AI. Each program of life-activity of an individual is repeatedly subjected to natural correction of program tasks in the life of a biophysical being. However, in recent years, scientists from different countries began to seek to reprogram the brain and find the real cause of death. Some biologists and evolutionists believe that this process is nonrandom and that it is controlled by a kind of “death program.” So they call a special set of genes, forcing the body to become decrepit and die, giving way to a new generation of their own kind. The aim of our work is to design new technologies and methods to adjust the life-activity programs from biophysical views, increasing the useful life of bodies by delaying destructive processes and the aging process. Our life-activity program is carried out through the device and IT programs in a mobile application, using contact/contactless frequency code effects on the brain, which is decoded and accepted by the human brain for execution (reprogramming), as a natural addition and an integral part of the brain work. Code programs are compiled according to the working algorithms of the Cosmo-terrestrial structure of life-activity of biophysical objects on the planet Earth. Our technology is one of the varieties of brain-computer technology.