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30 June 2019, Volume 2 Issue 2 Previous Issue    Next Issue
Postulation of a period of an unexplored manuscript —— Kashyapa Samhita
Divya Jyothi, Deepa K K
92Medical Data Mining. 2019, 2 (2): 50-55.   https://doi.org/10.12032/mdm2018018
Abstract ( 139 )     PDF (414KB) ( 70 )  
Fixing the date of an unexplored manuscript is always a challenging task for a research scholar. The chronology of an unpublished manuscript can be postulated based on internal and external evidence. Here is the study of a manuscript named Kashyapasamhita which is quite different from deemed Kashyapasamhita that is known off. The study was carried out by deciphering and critically editing six manuscripts collected from IPGT & RA (with accession no 6512 and 10779), Tanjore Sarasvati Mahal Library (with accession no.11045), Sampurnananda Library Varanasi (with accession no 1088604) and Oriental Research Institute Mysore (with accession no A129), MS University Baroda Library (with accession no 13474B). The study resulted in the exploration of the concepts regarding Desha (place), Nadi (pulse), Dosha (the three humours of the body), Daivavyapashravya Chikitsa (rituals related to god) and Rasayoga (mercurial formulations). The full paper details the postulation of a period of an unexplored manuscript -Kashyapa Samhita based on the chronology of available Ayurvedic classics.
Efficacy of empowerment education in self-management with Type 2 Diabetes Mellitus: A systematic review and meta-analysis
Yu-Di Cao, Ke-Jia Liu, Yue Hu , Li-Jiao Wei
92Medical Data Mining. 2019, 2 (2): 56-65.   https://doi.org/10.12032/mdm2018016
Abstract ( 136 )     PDF (1818KB) ( 44 )  
Objective: To evaluate the impact of empowerment education in self-management with Type 2 Diabetes Mellitus. Methods: A literature search was performed in PubMed, Web of Science, Cochrane Library, Embase, China National Knowledge Infrastructure (CNKI), WanFang Data, CQVIP and China Biology Medicine disc (CBMdisc) and for randomized controlled trials published before November 2018. RevMan5.3 software was used for metaanalysis. Results: A total of 11 articles were included, involving 1139 patients. The group of empowerment education included 574 participants, and the regular education groups 565 participants. Meta-analysis showed that the group of empowerment education has an advantage over the control group in the levels of self-efficacy [MD= 17.55, 95%CI(14.14, 20.96), P<0.00001], self-management [SMD=0.85, 95%CI(0.60,1.11),P<0.00001] , as well as the effectiveness of short-term empowerment education(within 6 months ) on reducing HbA1c ( P<0.05); however failed to long-term empowerment education (beyond 12 months) (P= 0.05). Conclusion: This meta-analysis indicates that empowerment education can be an acceptable and appropriated nursing intervention for type 2 diabetes mellitus patients.
Curcumin in The Treatment of in Animals Myocardial ischemia reperfusion: A Systematic review and Meta-analysis
Qian He, Bin Meng, Hong-Yun Hu, Gao-Jian Zhuang, Qun Tang, Xu Zhu
92Medical Data Mining. 2019, 2 (2): 66-75.   https://doi.org/10.12032/mdm2018019
Abstract ( 137 )     PDF (2923KB) ( 60 )  
Objective: The protective effects of curcumin on myocardial ischemia-reperfusion were systematically evaluated by analyzing the related literatures of curcumin and myocardial ischemia-reperfusion. Methods: The computer was searched for Wanfang, VIP, China National Knowledge Infrastructure(CNKI), SinoMed, and Pubmed database to find animal experiments on curcumin treatment of myocardial ischemia-reperfusion.The retrieval time is from the establishment of the database to November 2018. Two researchers independently screened the literature based on inclusion and exclusion criteria, extracted the data, and assessed the risk of bias in the included studies. Meta analysis was performed using RevMan 5.3 software. Results: Finally, 9 studies were included for analysis. Meta-analysis showed that the curcumin group can reduce LDH and MDA levels compared with the ischemiar-reperfusion group  (LDH: SMD=-4.75, 95% CI [-6.56, -2.94], P < 0.01, MDA: SMD=-2.27, 95% CI [-3.07, -1.47], P < 0.01), the difference was statistically significant (P<0.01). In the subgroup analysis of different doses of curcumin, different doses of curcumin (0.8, 10, 12.5, 20, 25, 30, 50 mg) were able to reduce LDH content compared with the ischemia-reperfusion group, and the differences were statistically significant. Different doses of curcumin (5,10,20,30,40mg) can reduce MDA content, and the difference is statistically significant; curcumin (0.8mg) group has no statistically significant effect on MDA content (SMD = -0.54, 95% CI [-1.35, 0.28], P = 0.20). The relationship between the content of MDA and the dose of curcumin showed that compared with the curcumin (20 mg) group, the curcumin (40 mg) group could better reduce the MDA content, and the difference was statistically significant (P=0.03). Conclusion: Curcumin can reduce the content of LDH and MDA in myocardial ischemia-reperfusion,  and has a protective effect on myocardium. Moreover,  the ability to reduce the damage is related to the dose of curcumin. However, the sample of the included studies is limited, and this conclusion requires more high-quality experiments to verify.
Bibliometric Analysis of the Elderly’s Frailty in China
Xiao-Hui An, Fu-Liang Sun, Shu-Qing Cao
92Medical Data Mining. 2019, 2 (2): 76-83.   https://doi.org/10.12032/mdm2018020
Abstract ( 131 )     PDF (593KB) ( 38 )  
Objective: To analysis the research status of the elderly's frailty in China by bibliometric, in order to provide  reference for clinical practices and nursing researches. Methods: Search  China National Knowledge Infrastructure (CNKI), WanFang Data, CQVIP, China Biology Medicine (CBM) disc to find the studies concerning frailty of older adults in China, and analysis the information of Published year, Provinces, Institutions, Journals, Types, Contents and Funds. Results: A Total of 248 articles were included in this study. From 2011, the numbe of studies about the elderly's  frailty was growing  rapidly;  the province with  the largest number of publications was Beijing, with a total of 82 articles; the institution with the largest number of publications was Beijing Hospital, with 20 articles; the journal with the largest number of publications was Chinese Journal of Geriatrics, with 27 articles; the research type with the largest number of articles was cross-sectional study, with 92 articles, whose content was mainly about the factors of frailty. Conclusion: The study on the elderly's frailty was just starting in China. Hoping to carry out interventional studies widely in the future, so as to delay the progress of frailty and improve the quality of life of the elderly.
The application effect of swaddling bath in neonates: A meta-analysis
Hui-Ping Wang, Chang-De Jin
92Medical Data Mining. 2019, 2 (2): 84-89.   https://doi.org/10.12032/mdm2018017
Abstract ( 204 )     PDF (493KB) ( 84 )  
Objective: The meta-analysis is to objectively evaluate the efficacy of swaddling in neonates. Methods: Randomized controlled trials (RCTs) and Randomized cross-over design (RCD) about the effects of swaddling in neonates from multiple electronic databases (PubMed, Web of Science, the Cochrane Library, EMBASE, CINAHL,CNKI, Wanfang and VIP) until January 2019. Two investigators independently screened eligible studies, extracted data, and assessed the methodological quality by using the quality evaluation criteria for RCTs recommended by Cochrane Handbook. Then data were analyzed by Rev Man 5.3. Results: A total of 6 papers (4 randomized controlled trials and 2 Randomized cross-over design) with 318 participants were included. The meta-analysis indicated that there was a significant difference on Body Temperature, Heart Rate, crying time, incidence of open eyes and incidence of closed eyes (P<0.05); There was no significant difference in Spo2 level between the two groups (p>0.05). Conclusion: Swaddling bath has little influence on the Body Temperature, Heart Rate, and behavioral response of newborn. And it has no significant effect on maintaining Spo2 level. However it can reduce the stress behavior of the newborn. Due to the limitations of the quality of studies included, multi-centered randomized controlled trial large sample size are needed in the future to evaluate the effects of prone position ventilation on neonatal respiratory distress syndrome.