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TMR Modern Herbal Medicine  2018, Vol. 1 Issue (3): 181-188    DOI: 10.12032/TMRmhm2017B25
Review     
Immunoregulation and anti-tumor effects of Polyporusus Bellatus: a review of recent research
Lin Miao-Miao1, Cui Mei-Yu1, Cao Hai-Yan1, Wu Xue-Song2, Cai Li-Jing1, Zhang Li-Hui1, Zhang Guo-Wei1,*()
1College of Chinese Medicine, Hebei University, Baoding, Hebei province, China
2Laiyuan hospital of Chinese Medicine, Laiyuan, Hebei province, China.
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We summarized the Polyporusus Bellatus (PPS) efficacy of immunomodulation, liver protection and anti-tumor, then provide scientific basis for further research and clinical application. This dissertation first overview relevant literatures of PPS recent years and describe comprehensively the research progress of the immunoregulation, liver protection and anti-tumor effects and mechanism of PPS. The review shows that the PPS play anti-tumor effects through antioxidation, scavenging free radicals, inhibiting tumor cell proliferation, inducing apoptosis, affecting tumor gene expressions and enhancing immune functions. PPS can exert immunoregulatory, hepatoprotective and anti-tumor effects through multiple pathways and multiple targets, which provides a good application prospect in clinic.

Highlights

Polyporusus Bellatus (PPS) is the major component of Zhuling (Polyporus). This dissertation first overview relevant literatures of PPS recent years. PPS has immunoregulation, liver protection and anti-tumor effect. PPS can exert immunoregulatory, hepatoprotective and anti-tumor effects through multiple pathways and multiple targets, which provides a good application prospect in clinic.



Key wordsPolyporusus Bellatus      Immunoregulation      Anti-tumor      review     
Received: 10 June 2018      Published: 25 July 2018
Fund:  The study was funded by the National Natural Science Foundation of Hebei (No.H2018201179). Hebei University of Science and Technology (No. QN2016077). Health and Family Planning Commission of Hebei (No. 20160388).
Corresponding Authors: Zhang Guo-Wei     E-mail: xxzgw@126.com
Cite this article:

Lin Miao-Miao, Cui Mei-Yu, Cao Hai-Yan, Wu Xue-Song, Cai Li-Jing, Zhang Li-Hui, Zhang Guo-Wei. Immunoregulation and anti-tumor effects of Polyporusus Bellatus: a review of recent research. TMR Modern Herbal Medicine, 2018, 1(3): 181-188. doi: 10.12032/TMRmhm2017B25

URL:

https://www.tmrjournals.com/mhm/EN/10.12032/TMRmhm2017B25     OR     https://www.tmrjournals.com/mhm/EN/Y2018/V1/I3/181

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