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9TMR Non-Drug Therapy  2019, Vol. 2 Issue (1): 13-19    DOI: 10.12032/TMRND201902005
Hypothesis of non-drug therapy     
Review of the non-drug treatment in obesity
Chang Liu1
1 Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
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The present review summarizes the non-drug treatment of obesity in recent years, to analyze their underlying mechanism and provide further guidance for clinical practitioners.

Editor’s Summary

For patients with obesity, weighing the advantages and disadvantages of various non-drug therapeutic methods and helping them choose the right method is the best way to fight obesity.


Obesity, which bring a great perplex to family and society, has significant contribution to the risk of diabetes, cardiovascular disease, and other comorbidities. In past four decades, the incidence of obesity has been on the alarming rise and so far about a third of the world's adults are affected by obesity. Due to the side effects and adverse reactions of drug treatment, obesity patients tend to select non-drug treatment. The present review summarizes the non-drug treatment of obesity in recent years, including acupuncture, exercise, surgery, lifestyle intervention and psychological guidance, to summarize their underlying mechanism and provide further guidance for clinical practitioners. Auricular acupuncture was proved to have the positively influence in Ghrelin, a novel obesity-related peptide hormone. Exercise could treat obesity by reducing the inflammatory factors associated with obesity. Furthermore, obesity surgery can not only reduce fat intake and nutrient absorption, but also inhibit the generation of Neuropeptide Y (NPY) by increasing the secretion of Peptide YY (PYY). Besides, breaking down psychological and behavioral barriers to lifestyle treatment of obesity will have a significant effect.

Key wordsObesity      Acupuncture      Exercise      Lifestyle      Surgery      Psychological      NPY      PPY     
Received: 20 February 2019      Published: 05 March 2019
Cite this article:

Chang Liu. Review of the non-drug treatment in obesity. 9TMR Non-Drug Therapy, 2019, 2(1): 13-19. doi: 10.12032/TMRND201902005

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Figure 1 Type of bariatric surgery [51]
Note: A, gastric band; B, gastric bypass; C, sleeve gastrectomy.
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