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Clinical Medicine Characteristics Study of Traditional Chinese Medicine in the treatment of cancer pain based on Data Mining
Hui-Li Shui, Zhu Yang, Feng-Xi Long, Wen-Qi Huang, Bing Yang, Zhen Zhang, Dong-Xin Tang,
92Medical Data Mining    2019, 2 (1): 39-49.   https://doi.org/10.12032/mdm2018014
Abstract PDF (762KB)  
Objective: To explore the clinical characteristics of traditional Chinese medicine in the treatment of cancer pain based on traditional Chinese medicine inheritance support system (TCMISS). Methods: China Chinese CNKI database, VIP database, Wanfang database (1979 - 2017) were searched to get the prescriptions for cancer pain treatment. At last, 290 prescriptions were got and used to, set up the cancer pain prescriptions database, The route of administration, medicinal properties and drug use frequency were analyzed, and the rules of drug use were analyzed by mining rules such as association rules and complex system entropy clustering. Results: A total of 286 drugs were involved, and the association rules of drug properties, taste, meridian tropism, drug frequency and drugs were defined, and 20 core combinations and 10 new prescriptions were developed. Conclusion: The clinical medication rule of Chinese medicine for treating cancer pain has been excavated, and its reflected drug philosophy of "Tong" is the main, the emphasis is on pain relief, "tonic" is the main, the emphasis is on harmony, qi and blood are treated together, the emphasis is on dredging, antitumor analgesic, treatment of symptoms and root causes is equally important.
Bloodletting Cupping Therapy for postherpetic neuralgia: a systematic review and meta-analysis
Qian Cui, Yu-Hui Ma, Xiao-Ming Jin, Lin-Feng Li, Guo-Wei Zhang
92Medical Data Mining    2018, 1 (2): 57-67.   https://doi.org/10.12032/mdm2018007
Abstract PDF (1808KB)  
Objective: To evaluate the clinical effects of bloodletting cupping therapy (BCT) for patients with postherpetic neuralgia. Methods: We comprehensively searched four Chinese databases (Wanfang, China National Knowledge Infrastructure, VIP Database for Chinese Technical Periodicals,China Biology Medicine disc) and foreign databases (Pubmed, Cochrane Library). The retrieval time was from the build-up time to May 2018. RevMan 5.3 software was used for statistical analysis. Results: We finally obtained 18 eligible studies. Compared with routine western medicine, BCT can significantly improve PHN (OR= 7.45, 95% CI, 3.36-16.51, Z=4.95, P < 0.01). BCT plus other methods of acupuncture with fire needle and filiform needle has significant therapeutic effect (OR=5.54, 95% CI, 3.01-10.19, P < 0.01), BCT plus routine western medicine has significant therapeutic effect (OR=4.99, 95% CI, 2.73-9.11, P<0.00001). Conclusion: It showed that the therapeutic effects of BCT, BCT plus other acupuncture methods with fire needle and filiform needle, and BCT combined with western medicine are better than those treated with single western medicine. It is effective to treat postherpetic neuralgia with Bloodletting Cupping Therapy.
The effects of TCM nursing intervention on the life quality of cancer patients with pain: a review of recent research
Pei-Yao Li, Yun-Lan Jiao, Chun-Hua Zhang, Ling Wang, Wen-Wen Zhao, Hui-Xin Ding, Chun-Guang Yu
9TMR Non-Drug Therapy    2019, 2 (2): 55-61.   https://doi.org/10.12032/TMRND201902007
Abstract HTML PDF (544KB)  

Highlights

As a complementary and alternative therapy to Western analgesics, traditional Chinese medicine nursing has unique advantages in relieving pain in patient with cancer and can effectively improve quality of life.

Editor’s Summary

The conventional analgesics are selected to relieve pain in patient with cancer; however, their adverse reactions seriously affect the patient’s quality of life (QOL). Traditional Chinese medicine nursing can improve clinical symptoms and QOL through massage, external treatment of Chinese herbs, auricular therapy, etc. as well as reduce the toxic side effects of analgesics, making it worthy of clinical popularization and application.

Abstract

Tumor pain is common in patients with advanced cancer, 70-80 % have varying degrees of pain. Treatment of cancer pain has become a difficult issue in oncology, poor pain control often seriously affects the patients' quality of life (QOL). Traditional Chinese medicine (TCM) nursing intervention can improve symptoms and QOL through massage, external treatment of TCM, and auricular therapy, which have unique curative effects such as regulating Qi (a vital force that forms part of living entity in traditional Chinese culture) and blood, stabilizing the mind, and enhancing immunity. Not only does TCM nursing intervention prevent disease but also cultivates the mind, helps achieve systemic relaxation, and reduces the pain of cancer patients and the toxic side effects of painkillers, so as to improve QOL and satisfaction, making it worthy of clinical popularization and application. At present, there is an urgent need to carry out high-quality, multi-center, large-sample randomized controlled trials and develop a standardized TCM nursing intervention implementation scheme and efficacy standards to promote its application.

The clinical progress and potential mechanism of massage therapy on knee osteoarthritis
Dong Si-Jia, Zhang Chi, Wu Jia-Hang, Yin Hao
TMR Non-Drug Therapy    2018, 1 (1): 2-8.   https://doi.org/10.12032/TMRND201801002
Abstract HTML PDF (718KB)  

Highlights

The effectiveness of massage is superior to that of joint cavity injection while the integrated therapeutic method containing massage is superior to that of single massage.

Editor’s Summary

Massage plays a key role in the non-drug therapy of knee osteoarthritis.

Abstract

Knee osteoarthritis (KOA) is a disease due to the degenerative pathological change of knee joint, which commonly occurs in the elderly. The main clinical characters of KOA are the pain, stiffness, and dysfunction of knee joint. Western medicine regarding to the treatment of KOA aims to relieve the pain and delay the progress of disease such as intra-articular injection and functional exercise. Traditional Chinese medicine (TCM) therapy includes massage, herb, acupuncture, microwave, etc. Among them, the massage technique has the advantages of simpleness, effectiveness and non-invasive manipulation. The present study compared the curative effects of different therapies on KOA including Western medicine therapeutic method, single massage, complementary TCM therapeutic method containing massage and integrated TCM and western medicine therapeutic method containing massage. We found that the effectiveness of single massage method is better than that of joint cavity injection. The effectiveness of massage in combination with herb and acupuncture is better than that of massage alone. The effectiveness of joint cavity injection or functional exercise combined with massage and acupuncture is better than that of the single articular cavity injection or functional exercise. However, more research and clinical trials are still needed to determine the exact mechanism of massage.

Prone-positioned upside-done arch exercise, a kind of lumbodorsal muscles training, curbs the progression of lumbar disc bulge
Gao Zeng-Jie, Chen Jiu-Yi, Liu Yang
TMR Non-Drug Therapy    2018, 1 (1): 9-15.   https://doi.org/10.12032/TMRND201801003
Abstract HTML PDF (964KB)  

Highlights

The comprehensive therapy containing prone- positioned upside-done arch exercise showed beneficial effects in patients with lumbar disc bulge in the terms of visual analogue score, bulge size and straight leg raise test.

Editor’s Summary

As a nonoperative treatment for lumbar disc herniation, lumbodorsal muscle training has the potentials to provide better prevention measures for lumbar disc bulge.

Abstract

Objective: To study the effects of prone-positioned upside-done arch exercise, a kind of lumbodorsal muscles training originated from Yoga, on curbing the progression of lumbar disc bulge. Methods: A total of 120 out-patients, diagnosed with lumbar disc bulge by CT and/or MRI, were randomly divided into the observation group and the control group, with 60 patients in each group. Patients in the observation group received the prone-positioned upside-done arch exercise combined with traction and acupuncture for two months and followed with a two-year treatment with prone-positioned upside-done arch exercise while the patients in the control group only received traction and acupuncture for two months. After two years, patients in both groups were investigated for the visual analogue score, MR image and straight leg raise tests. Results: Compared to the control group, prone-positioned upside-done arch exercise combined with traction and acupuncture showed significant decrease in patients’ visual analogue score, bulge size and the positive ratio of straight leg raise test (P = 0.001, P = 0.001 and P = 0.02 respectively), suggesting the inhibitory effect on the progression of lumber disc bulge. Conclusion: Prone-positioned upside-done arch has the potentials to protect patients with lumbar disc bulge from nerve root compression syndrome.

Comparative study for cardiovascular risk factors of rheumatoid arthritis and osteoarthritis
Yue Cai-Ping, Li Ming-Xi, Liu Yan, Li Fang-Kai, Liu Xiao-Ping, Ma Jun-Fu, Zhu Yue-Lan, Hou Xiu-Juan
TMR Non-Drug Therapy    2018, 1 (1): 16-22.   https://doi.org/10.12032/TMRND201801004
Abstract HTML PDF (714KB)  

Highlights

Patients with rheumatoid arthritis have higher incidence rate of cardiovascular diseases than those with osteoarthritis.

Editor’s Summary

This study focuses on the effects of non-traditional risk factors on the incidence rate of cardiovascular diseases in patient with rheumatoid arthritis, including inflammation indexes, echocardiography and carotid ultrasound related indexes etc.

Abstract

Objective: To compare the difference of cardiovascular risk factors in patients with rheumatoid arthritis (RA) and osteoarthritis (OA). Methods: A retrospective analysis was performed to compare the difference of cardiovascular factors between 44 patients with RA and 36 patients with OA in terms of their gender, age, body mass index, course of disease, carotid ultrasound related indicators, homocysteine, blood lipid levels, inflammation index, echocardiographic index, etc. Results: (1) General situation: there was no significant difference between two groups in terms of gender and age (P > 0.05). However, body mass index of OA group was significantly higher than that of RA group and the course of disease of RA group was significantly longer than that of OA group (P = 0.024). (2) Laboratory index: the level of homocysteine of RA group was significantly higher than that of OA group (P = 0.002). Though there was no significant difference between these two groups in terms of total cholesterol, triglyceride, low density lipoprotein, apolipoprotein B and high density lipoprotein (P > 0.05), the level of apolipoprotein A1 of RA group was significantly lower than that of OA group (P < 0.001) and the level of lipoprotein A of RA group was significantly higher than that of OA group (P < 0.001). The levels of erythrocyte sedimentation rate and C reactive protein of group RA were significantly higher than those of OA group (P < 0.001). (3) Stroke volume and ejection fraction of echocardiography of RA patients were significantly lower than those of OA patients (P = 0.022, P = 0.009). However, there was no significant difference between two groups in terms of aortic diameter, left atrial diameter, left ventricular end diastolic diameter, left ventricular end systolic diameter, left ventricular posterior wall thickness, left ventricular fractional shortening, right ventricular diameter, right atrial diameter, and interventricular septum thickness (P > 0.05). Though significant difference in carotid artery plaque incidence between the two groups was not observed (P > 0.05), the incidence of carotid artery thickening and carotid artery middle thickness were significantly different between the two groups (P < 0.001). Conclusion: The rate for the occurrence of cardiovascular events in patients with RA was higher than those with OA. Additionally, effective control of RA patients’ conditions has the potential to reduce the risk of cardiovascular events.

Acupuncture therapy in a patient with radial nerve injury
Tan Zheng, Jin Yu, Lan Zhao-Xi
TMR Non-Drug Therapy    2018, 1 (1): 23-27.   https://doi.org/10.12032/TMRND201801005
Abstract HTML PDF (728KB)  

Highlights

Acupuncture treatment has the potentials to stimulate Qi-blood circulation and short the course of radial nerve injury.

Editor’s Summary

Acupuncture plays a key role in the non-drug therapy of radial nerve injury.

Abstract

Objective: To analyze the cause and pathogenesis of nerve injury and find out the suitable acupuncture points. Methods: Acupuncture at the unilateral points of Hegu (LI4), Waiguan (TB5), Shousanli (LI10), Quchi (LI11) and the bilateral points of Zusanli (ST36), accompanied by method of electro-acupuncture. Results: After three courses of acupuncture treatment (30 minutes each time, 6 times each course), the patient presented the symptoms of making a fist strongly, disappearance of wrist drop, and positive sign of lifting wrist assay in turn. Simutaneously, the grip strength of hand increased and the strength of muscle reach over level 4. Conclusion: With the help of electro-acupuncture, acupuncture therapy can relieve pain, improve the local blood supply of nerve injury and then repair the damage of the nerve.

Based on the theory of traditional Chinese and western medicine for the co-treatment of neck, chest, and waist
Zhang Kai, Wu Xin
TMR Non-Drug Therapy    2018, 1 (3): 87-95.   https://doi.org/10.12032/TMRND201801013
Abstract HTML PDF (1477KB)  

Highlights

This paper expounds the scientific nature of “the co-treatment of the neck, chest, and waist” from the perspective of traditional Chinese medicine theory and modern medical research.

Editor’s Summary

This review proposes a new approach in cervical diseases in terms of the co-treatment of the neck, chest, and waist, which not only improves clinical efficiency but also decrease recurrence rate.

Abstract

Cervical diseases are frequently occurring diseases. Currently, the local physical therapy is the most commonly suggested treatment method. We believe that cervical spine lesion cause spinal instability and then the physiological function of the thoracic and lumbar spine is also affected by it. Therefore, the study on cervical lesions should not be limited to the local part of the cervical spine but should extend to the restoration of stability of the spine, to achieve the same curative effects on the chest and waist. Therefore, we propose a new concept for the co-treatment of the neck, chest, and waist. The concept of this proposed therapy is based on three theoretical aspects: syndrome differentiation, disease prevention, and Du meridian and its relationship with other meridians. This was elaborated from the perspective of spinal static balance, anatomy, epidemiological evidence, and biochemistry. The relationship between cervical vertebral lesions and thoracic and lumbar vertebral lesions indicates the scientific nature of the “co-treatment of the neck, chest, and waist”. This article also summarizes the methods of non-drug therapy under the guidance of this theory.

Systematic evaluation and trial sequential analysis of warming acupuncture combined with joint mobilization in the treatment of scapulohumeral periarthritis
Tian Rong, Li Da, Han Yu-Hui, Fan Yi-Hua
TMR Non-Drug Therapy    2018, 1 (3): 96-108.   https://doi.org/10.12032/TMRND201801014
Abstract HTML PDF (1846KB)  

Highlights

Warming acupuncture combined with joint mobilization had a significant effect on the treatment of scapulohumeral periarthritis.

Editor’s Summary

This review provides a new combination of non-drug therapy in the treatment of scapulohumeral periarthritis.

Abstract

Objective: To evaluate the clinical efficacy of warming acupuncture combined with joint mobilization for the treatment of scapulohumeral periarthritis. Methods: A search for published randomized controlled trials (RCT) investigating warming acupuncture combined with joint mobilization for the treatment of scapulohumeral periarthritis was performed using the Cochrane Library, PubMed, Embase, and Web of Science databases. According to requirements of the Cochrane systematic review, all evaluations of RCT investigating warming acupuncture with joint mobilization in the treatment of scapulohumeral periarthritis were performed via method quality assessment, data extraction, and data analysis. Revman 5.3 and Stata 12.0 statistical software were used for the meta-analysis, and the trial sequential analysis (TSA) software estimated the required information size for each outcome. Results: A total of 14 articles were retrieved for meta-analysis, which included 551 cases in the treatment group and 539 cases in the control group. Meta-analysis showed that: (1) warming acupuncture combined with joint mobilization improved total efficiency [OR = 6.16, 95% CI (3.79, 10.00), Z = 7.34; P < 0.001), TSA results confirmed the results of the meta-analysis; (2) warming acupuncture combined with joint mobilization improved the cure rate [OR = 2.84, 95% CI (2.19, 3.70), P < 0.001], TSA results revealed that no further tests were needed to verify; (3) warming acupuncture combined with joint mobilization reduced the number of treatments required for healing [MD = -7.49, 95% CI (-9.75, -5.23), P < 0.001], TSA results confirmed the results of the meta-analysis; (4) in comparing visual analog scale scores before and after treatment, meta-analysis result showed that: SMD = -2.01, 95%CI (-2.37, -1.65), P < 0.001, the difference was statistically significant, TSA results confirmed the results of the meta-analysis. Conclusion: Warming acupuncture combined with joint mobilization had a significant effect on the treatment of scapulohumeral periarthritis.

Therapeutic effect of different treatment methods on functional anorectal pain
Li Hua-Juan, Wei Zhi-Jun, Wu Xi-Hua
9TMR Non-Drug Therapy    2018, 1 (4): 131-137.   https://doi.org/10.12032/TMRND201801019
Abstract HTML PDF (1597KB)  

Highlights

Non-drug therapy including acupuncture and physical exercise can enhance the clinical efficacy of single Chinese medicine in the treatment of functional anorectal pain.

Editor’s Summary

Because pain is a main subjective symptom of patient with functional anorectal pain, the role of non-drug therapy in pain remission has an advantage and is worthy of further research.

Abstract

Objective: To observe the clinical efficacy of oral traditional Chinese medicine (Jiaweitiaoqi decoction), electroacupuncture, biofeedback, and combined treatment on functional anorectal pain (FAP). Methods: A total of 200 patients with FAP were randomly divided into 4 groups, with 50 patients in each group. Group 1 was given oral Jiaweitiaoqi decoction; group 2 was given electroacupuncture at the lumbosacral acupoints; group 3 was given biofeedback training; and group 4 was given combined treatment. The numeric rating scale (NRS), Short Form-36 (SF-36) quality of life scale, static pressure of the anal canal, and maximum systolic pressure were observed in the 4 groups. Results: The observation indices of the 4 groups were all improved after treatment compared with those before treatment, and the fourth group showed the most obvious improvement. Regarding NRS scores, the static pressure of the anal canal, and maximum systolic pressure, group 4 had lower values than the other 3 groups (P < 0.05 for all). In the SF-36 quality of life score, group 4 showed a higher value than the other 3 groups (P < 0.05). Conclusion: Non-drug therapy including acupuncture and physical exercise can enhance the clinical efficacy of single Chinese medicine in the treatment of FAP.

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