This paper gives a brief overview of the evolutionary history of human diet, discusses various reasons why some modern humans choose to abstain from eating animal products, and explores the psychological effects occasioned by the eating of meat. The authors argue that when modern, scientifically literate humans choose to eat meat and animal-milk-based products, while being simultaneously aware of the associated poor outcomes in terms of personal health, environmental sustainability, and animal suffering, then psychological stress is an inevitable outcome. They highlight some key recent additions to the growing body of evidence which demonstrates that the choice to eat meat is a factor in environmental destruction, animal misery, and personal health risks, and explore the causes and consequences of the predictable psychological stresses that result for those individuals who continue to habitually eat meat.
Highlights: In this paper, various factors related to Hashimoto’s thyroiditis and thyroid cancer, especially papillary thyroid cancer, morbidity and lymph node metastasis, are reviewed concerning recent literature.
Editor’s Summary: In recent decades, it is very high for the incidence of HT and the thyroid cancer rate. This article is more likely that autoimmune thyroid inflammation such as HT is carcinogenic, and thyroid dysfunction related to HT may also promote tumor growth induced by stimulating TSH receptor.
Abstract: In recent years, the incidence of Hashimoto’s thyroiditis and thyroid cancer has shown a rapid growth trend. These two diseases have severely affected the public health. Many epidemiological studies have shown that thyroid cancer is often associated with Hashimoto’s thyroiditis. Hashimoto’s thyroiditis may promote the occurrence of thyroid cancer, as well as affecting the progression of the tumor, lymph node metastasis, and even the prognosis of patients. In this paper, the relationship between Hashimoto’s thyroiditis and thyroid cancer and the pathogenesis of thyroid cancer are reviewed regarding molecular mechanism, clinical pathology, and serology.
Spleen deficiency is often accompanied by dampness. Cytokines, immunoglobulins, and gastrointestinal hormones play major roles in the pathogenesis of spleen deficiency and dampness.
The two TCM syndromes “spleen deficiency” and “dampness” were cause and effect to each other.
Objective: To explore the essence of spleen deficiency and dampness in Chinese medicine by successfully constructing a rat model with this syndrome. Methods: Rat models with the syndrome of dampness and spleen deficiency were established with the use of a high-fat, low-protein diet and excessive fatigue induced by loaded swimming. A total of 25 common clinical serological markers were tested. The T test, rank test, and partial least squares regression-discriminant analysis were used to analyze the data. Results: Total protein, albumin, motilin, interferon-γ, interleukin-2, immunoglobulin A, immunoglobulin G, and complement 3 levels in the model rats were lower than those in the control group (P = 0.029, P = 0.032, P < 0.001, P < 0.001, P < 0.001, P < 0.001, P < 0.001, P < 0.001, respectively). The serum creatinine, total cholesterol, aldosterone, antidiuretic hormone, gastrin, interleukin-4, somatostatin, atrial natriuretic peptide, and vasoactive intestinal peptide levels in the model group were higher than those in the control group (P < 0.001, P = 0.015, P < 0.001, P < 0.001, P < 0.001, P < 0.001, P < 0.001, P < 0.001, P < 0.001, respectively). There was no statistical difference between the two groups in aspartate transaminase, alanine aminotransferase, globulin, albumin/globulin, blood urea nitrogen, high-density lipoprotein, and low-density lipoprotein. The model animal syndrome used two important variables in analysis with partial least squares regression-discriminant analysis. At the same time, the two dimensions were difficult to distinguish for each biological index. Conclusion: Spleen deficiency is often associated with dampness. The index that represents spleen deficiency can also represent dampness. Cytokines, immunoglobulins, and gastrointestinal hormones play a major causative role in both spleen deficiency and dampness.
Dendrobium officinale polysaccharides has the protective effect of on photoaging human skin fibroblasts via removing ROS induced by UVB, inhibiting the secretion of MMP-1 and increasing the expression of TGF-β1.
Tiepishihu (Dendrobium officinale Kimura et Migo) was first recorded in Shennongbencaojing in the Qin and Han Dynasty of China (221 B.C.-25 A.D.).
The purpose of this study was to explore the protective effect of Dendrobium officinale polysaccharides (DOP) on photoaging human skin fibroblasts and its specific mechanism of action. The photoaging fibroblast model was established by ultraviolet B (UVB) irradiation. The toxic effects of different concentrations of DOP were detected using MTT. Senescent cells were detected using a β-galactosidase kit. Reactive oxygen species (ROS) in cells were detected using a flow cytometer. The expression of matrix metalloproteinase-1 (MMP-1), type I collagen C-terminal peptide (CICP), and transforming growth factor β-1 (TGF-β1) in spent culture medium was detected by ELISA. The results showed that the low concentration of DOP (20, 40, 80 μg/mL) had no cytotoxicity on fibroblasts. After 60 mJ/cm2 UVB irradiation, the number of aging β-gal-positive cells increased, the levels of CICP and TGF-β1 in spent culture medium decreased, while the levels of MMP-1 and ROS increased. After administration of DOP on photoaging fibroblasts, the number of aging β-gal-positive cells decreased, the levels of ROS and MMP-1 decreased, and the levels of TGF-β1 and CICP increased. This experiment suggests that DOP has the effect of removing ROS induced by UVB, regulating the balance of collagen production and degradation, and protecting photoaging human skin fibroblasts.
Thunder-Fire moxibustion with ovulation monitoring significantly improved the pregnancy rate of patients diagnosed with adenomyosis- associated infertility.
Thunder-Fire moxibustion stemmed from the Taoism magic arts before the Yuan Dynasty of China (1271 A.D.-1368 A.D.) and took shape in the middle of the Ming Dynasty of China (1368 A.D.-1644 A.D.).
This study evaluated the clinical efficacy of Thunder-Fire moxibustion combined with ovulation monitoring for the treatment of adenomyosis-associated infertility. A series of 120 patients diagnosed with uterine adenomyosis and infertility and cold coagulation blood stasis syndrome in traditional Chinese medicine (with the clinical manifestations of premenstrual or menstrual lower abdomen cold pain, pain reduction with heat application, and cold extremities) were randomized equally to treatment group with Thunder-Fire moxibustion and ovulation monitoring as well as control group with ovulation monitoring only. Treatment continued for six menstrual cycles. The pregnancy rate of the treatment group was significantly increased with the control group (50.0% vs. 23.3%, P = 0.021). Dysmenorrhea and the traditional Chinese medicine syndrome in the treatment group improved significantly compared with the control group (3.87 ± 2.03 vs. 5.70 ± 1.01, P = 0.002 and 7.33 ± 4.11 vs. 10.52 ± 2.33, P = 0.006, respectively), and there was also significant between-group differences in serum cancer antigen 125 (55.45 ± 14.65 vs. 63.34 ± 11.41, P = 0.031). However, the average uterus diameters in the treatment and control groups were not significantly different (67.13 ± 7.59 vs. 69.89 ± 5.30, P = 0.137). Thunder-Fire moxibustion with ovulation monitoring improved the pregnancy rate of patients diagnosed with adenomyosis-associated infertility.
Copyright © TMR Publishing Group. All rights reserved.