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吴门验方 “ 阳和散结汤 ” 治疗乳腺癌理论浅析
成艳丽 彭涛 张国华
经典中医研究    2018, 1 (1): 9-12.   https://doi.org/10.12032/CCMR20180103
Abstract ( 2521 PDF (861KB) ( 590 )  
乳腺癌是女性最高发的恶性肿瘤,其发病率逐年上升,严重危害女性身心健康。吴雄志教授从事中医临床工作近 20 年,对肿瘤疾病有深刻的认识,所拟吴门验方 阳和散结汤 注重乳腺癌的病因与病位,采用中西汇通的思想,提高了对乳腺癌的治疗效果。
泽漆汤在肺癌治疗中的加减应用
彭涛
经典中医研究    2018, 1 (1): 5-8.   https://doi.org/10.12032/CCMR20180102
Abstract ( 2324 PDF (668KB) ( 553 )  
《金匮要略》泽漆汤治疗肺癌有一定临床疗效。笔者学习吴雄志教授使用泽漆汤治疗肺癌的理论和医案,结合自己临床使用的经验,从方药解析、合方加减、专病专药三方面展开论述,简要阐明泽漆汤在肺癌治疗中的方义和加减变化。
Whether Chinese physiognomy has scientific basis?
Life Research editorial group
90Life Research    2018, 1 (1): 30-31.   https://doi.org/10.12032/life2018-0711-006
Abstract ( 1964 HTML PDF (798KB) ( 469 )  
The implicit stress of eating meat
Christopher Anthony David, Peter Gerard Coan
90Life Research    2018, 1 (1): 9-17.   https://doi.org/10.12032/life2018-0711-003
Abstract ( 1327 HTML PDF (6125KB) ( 287 )  

This paper gives a brief overview of the evolutionary history of human diet, discusses various reasons why some modern humans choose to abstain from eating animal products, and explores the psychological effects occasioned by the eating of meat. The authors argue that when modern, scientifically literate humans choose to eat meat and animal-milk-based products, while being simultaneously aware of the associated poor outcomes in terms of personal health, environmental sustainability, and animal suffering, then psychological stress is an inevitable outcome. They highlight some key recent additions to the growing body of evidence which demonstrates that the choice to eat meat is a factor in environmental destruction, animal misery, and personal health risks, and explore the causes and consequences of the predictable psychological stresses that result for those individuals who continue to habitually eat meat.

Advances in the relationship between Hashimoto’s thyroiditis and thyroid cancer
Yu Qiao
93TMR Cancer    2018, 1 (3): 66-73.   https://doi.org/10.12032/TMRC201800031
Abstract ( 1261 HTML PDF (883KB) ( 380 )  

Highlights: In this paper, various factors related to Hashimoto’s thyroiditis and thyroid cancer, especially papillary thyroid cancer, morbidity and lymph node metastasis, are reviewed concerning recent literature.

Editor’s Summary: In recent decades, it is very high for the incidence of HT and the thyroid cancer rate. This article is more likely that autoimmune thyroid inflammation such as HT is carcinogenic, and thyroid dysfunction related to HT may also promote tumor growth induced by stimulating TSH receptor.

Abstract: In recent years, the incidence of Hashimoto’s thyroiditis and thyroid cancer has shown a rapid growth trend. These two diseases have severely affected the public health. Many epidemiological studies have shown that thyroid cancer is often associated with Hashimoto’s thyroiditis. Hashimoto’s thyroiditis may promote the occurrence of thyroid cancer, as well as affecting the progression of the tumor, lymph node metastasis, and even the prognosis of patients. In this paper, the relationship between Hashimoto’s thyroiditis and thyroid cancer and the pathogenesis of thyroid cancer are reviewed regarding molecular mechanism, clinical pathology, and serology.

Rat model for study of the essence of spleen deficiency and dampness in Chinese medicine
Xiao-Chun Han, Xu-Ming Ji, Lin Liu, Shuang Zhang, Li Sun, Qiu-Jian Feng, Shi-Jun Wang
Traditional Medicine Research    2018, 3 (5): 251-257.   https://doi.org/10.12032/TMR201813084
Abstract ( 1176 HTML PDF (1006KB) ( 249 )  

Highlights

Spleen deficiency is often accompanied by dampness. Cytokines, immunoglobulins, and gastrointestinal hormones play major roles in the pathogenesis of spleen deficiency and dampness.

Editor’s Summary

The two TCM syndromes “spleen deficiency” and “dampness” were cause and effect to each other.

Abstract

Objective: To explore the essence of spleen deficiency and dampness in Chinese medicine by successfully constructing a rat model with this syndrome. Methods: Rat models with the syndrome of dampness and spleen deficiency were established with the use of a high-fat, low-protein diet and excessive fatigue induced by loaded swimming. A total of 25 common clinical serological markers were tested. The T test, rank test, and partial least squares regression-discriminant analysis were used to analyze the data. Results: Total protein, albumin, motilin, interferon-γ, interleukin-2, immunoglobulin A, immunoglobulin G, and complement 3 levels in the model rats were lower than those in the control group (P = 0.029, P = 0.032, P < 0.001, P < 0.001, P < 0.001, P < 0.001, P < 0.001, P < 0.001, respectively). The serum creatinine, total cholesterol, aldosterone, antidiuretic hormone, gastrin, interleukin-4, somatostatin, atrial natriuretic peptide, and vasoactive intestinal peptide levels in the model group were higher than those in the control group (P < 0.001, P = 0.015, P < 0.001, P < 0.001, P < 0.001, P < 0.001, P < 0.001, P < 0.001, P < 0.001, respectively). There was no statistical difference between the two groups in aspartate transaminase, alanine aminotransferase, globulin, albumin/globulin, blood urea nitrogen, high-density lipoprotein, and low-density lipoprotein. The model animal syndrome used two important variables in analysis with partial least squares regression-discriminant analysis. At the same time, the two dimensions were difficult to distinguish for each biological index. Conclusion: Spleen deficiency is often associated with dampness. The index that represents spleen deficiency can also represent dampness. Cytokines, immunoglobulins, and gastrointestinal hormones play a major causative role in both spleen deficiency and dampness.

The protective effect of Dendrobium officinale polysaccharides on photoaging fibroblasts by scavenging reactive oxygen species and promoting the expression of TGF-β1
Rui Tang, Qia-Qia Li, Di Wang, Jing Chen, Jin-Hua Huang, Qing-Hai Zeng
1Traditional Medicine Research    2018, 3 (3): 131-139.   https://doi.org/10.12032/TMR201811071
Abstract ( 1070 HTML PDF (893KB) ( 224 )  

Highlights

Dendrobium officinale polysaccharides has the protective effect of on photoaging human skin fibroblasts via removing ROS induced by UVB, inhibiting the secretion of MMP-1 and increasing the expression of TGF-β1.

Editor’s Summary

Tiepishihu (Dendrobium officinale Kimura et Migo) was first recorded in Shennongbencaojing in the Qin and Han Dynasty of China (221 B.C.-25 A.D.).

Abstract

The purpose of this study was to explore the protective effect of Dendrobium officinale polysaccharides (DOP) on photoaging human skin fibroblasts and its specific mechanism of action. The photoaging fibroblast model was established by ultraviolet B (UVB) irradiation. The toxic effects of different concentrations of DOP were detected using MTT. Senescent cells were detected using a β-galactosidase kit. Reactive oxygen species (ROS) in cells were detected using a flow cytometer. The expression of matrix metalloproteinase-1 (MMP-1), type I collagen C-terminal peptide (CICP), and transforming growth factor β-1 (TGF-β1) in spent culture medium was detected by ELISA. The results showed that the low concentration of DOP (20, 40, 80 μg/mL) had no cytotoxicity on fibroblasts. After 60 mJ/cm2 UVB irradiation, the number of aging β-gal-positive cells increased, the levels of CICP and TGF-β1 in spent culture medium decreased, while the levels of MMP-1 and ROS increased. After administration of DOP on photoaging fibroblasts, the number of aging β-gal-positive cells decreased, the levels of ROS and MMP-1 decreased, and the levels of TGF-β1 and CICP increased. This experiment suggests that DOP has the effect of removing ROS induced by UVB, regulating the balance of collagen production and degradation, and protecting photoaging human skin fibroblasts.

Evaluating the clinical efficacy of Thunder-Fire moxibustion combined with ovulation monitoring in the treatment of adenomyosis combined with infertility
Hua Wang, Yan Chen, Yong Yin, Chun-Hua Cao, Sai-Li Wang, Qin Wang, De-Xi Peng, Chun-Jian Zhu, Lin-Wei Chen
Traditional Medicine Research    2018, 3 (5): 243-250.   https://doi.org/10.12032/TMR201813083
Abstract ( 956 HTML PDF (334KB) ( 180 )  

Highlights

Thunder-Fire moxibustion with ovulation monitoring significantly improved the pregnancy rate of patients diagnosed with adenomyosis- associated infertility.

Editor’s Summary

Thunder-Fire moxibustion stemmed from the Taoism magic arts before the Yuan Dynasty of China (1271 A.D.-1368 A.D.) and took shape in the middle of the Ming Dynasty of China (1368 A.D.-1644 A.D.).

Abstract

This study evaluated the clinical efficacy of Thunder-Fire moxibustion combined with ovulation monitoring for the treatment of adenomyosis-associated infertility. A series of 120 patients diagnosed with uterine adenomyosis and infertility and cold coagulation blood stasis syndrome in traditional Chinese medicine (with the clinical manifestations of premenstrual or menstrual lower abdomen cold pain, pain reduction with heat application, and cold extremities) were randomized equally to treatment group with Thunder-Fire moxibustion and ovulation monitoring as well as control group with ovulation monitoring only. Treatment continued for six menstrual cycles. The pregnancy rate of the treatment group was significantly increased with the control group (50.0% vs. 23.3%, P = 0.021). Dysmenorrhea and the traditional Chinese medicine syndrome in the treatment group improved significantly compared with the control group (3.87 ± 2.03 vs. 5.70 ± 1.01, P = 0.002 and 7.33 ± 4.11 vs. 10.52 ± 2.33, P = 0.006, respectively), and there was also significant between-group differences in serum cancer antigen 125 (55.45 ± 14.65 vs. 63.34 ± 11.41, P = 0.031). However, the average uterus diameters in the treatment and control groups were not significantly different (67.13 ± 7.59 vs. 69.89 ± 5.30, P = 0.137). Thunder-Fire moxibustion with ovulation monitoring improved the pregnancy rate of patients diagnosed with adenomyosis-associated infertility.

基于伤寒六经辨证之三阴病辨治溃疡性结肠炎理论探讨
徐晓
经典中医研究    2018, 1 (1): 1-4.   https://doi.org/10.12032/CCMR20180101
Abstract ( 871 PDF (790KB) ( 443 )  
溃疡性结肠炎是病因不明的难治性疾病,现代医学应用糖皮质激素、 甚至生物制剂可以有效缓解炎症反应,控制病情,但是此类药物需长期应用并且可导致肝肾损害、使人体长期处于免疫抑制状态等副作用日渐明显,临床观察采用中西医结合方法治疗溃结取得显著疗效,本文尝试从《伤寒论》六经之三阴病角度阐述溃疡性结肠炎各个阶段的病理变化,意为启发思维。
柴苓汤治疗 2 例儿童支原体肺炎的观察
李玉林
经典中医研究    2019, 2 (1): 14-17.   https://doi.org/10.12032/CCMR20190104
Abstract ( 863 PDF (1206KB) ( 481 )  
目的 : 使用小柴胡汤合上五苓散(柴苓汤)治疗支原体肺炎。方法 : 小柴胡汤和解少阳枢机,五苓散通调三焦水道,从水液输布代谢链治疗支原体肺炎。结果 :2 例支原体肺炎患儿使用柴苓汤后,体温恢复正常,肌体不适感消除。结论 : 柴苓汤治疗支原体引发的儿童高热、咳嗽、肺炎疗效确切,合方有效