The present scoping review provides evidence for the application of leech therapy in the treatment of plastic and reconstructive surgery, musculoskeletal diseases, osteoarthritis, etc..
The first recorded report of the use of leeches is in a medical poem, Alexipharma, for Nicander of Colophon, born 200 B.C.. There is also evidence of the using leeches by large scholars such as Avicenna in The Canon of Medicine and Abd-el-Latif al-Baghdadi in Al-Mukhtarat fi al-Tibb. Barbers-surgeons in the middle ages used to use leeches to shed blood for treating some kind of diseases. With the development of modern medicine, the first use of medical leeches occurred in the 1960's, for intravenous congestion after reconstructive surgery. In 2004 the FDA approved leech therapy to accelerate tissue transplantation.
After the developments of modern medicine, leeches were not used as before, but in the late nineteenth century, leeches were still being used in many countries around the world. Until now, leeches have been used to treat a wide range of diseases. The present study, is a scoping review of the evidence of the indication of leech therapy. The results of this study are based on English articles and dissertations published in databases from 2000 up to July 10, 2017. The results showed that leech therapy could be used in different conditions including venous congestion in plastic and reconstructive surgery, osteoarthritis, cardiovascular diseases due to blood coagulation disorders, migraine headache, skin disorders, diabetic foot ulcers, macroglossia, priapism, cancer complications, and wounds. More researches are needed in wider areas with more precise methodologies to ensure the potential therapeutic effects of leech therapy.
Medical cupping treatment can effectively alleviate metabolic indices and subcutaneous fat thickness at the abdomen in patients with metabolic syndrome and abdominal obesity.
The combination of cupping and Chinese medicine can help prolong the therapeutic effect and reduce the frequency of treatment in the management of metabolic syndrome.
Objective: To observe the clinical effects of medical cupping for metabolic syndrome (MetS) with abdominal obesity. Methods: In total, 75 patients with MetS with abdominal obesity were randomly divided into three groups: medical cupping, acupuncture, and waiting. Patients in the medical cupping group received smearing of Chinese medicine and cupping twice a week for 8 weeks. Patients in the acupuncture group received acupuncture on regulating the Dai meridian three times a week for 8 weeks. The waiting group was observed without any intervention. Changes in metabolic indices, including waist circumference (WC), blood pressure, fasting triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), fasting blood glucose (FBG), 2-h blood glucose (2hBG), and subcutaneous fat thickness were observed and compared before and after treatment among the three groups. Results: After the treatment, the WC, TG, FBG, and 2hBG in the medical cupping and acupuncture groups were lower than those in the waiting group. No difference was observed between the medical cupping and acupuncture groups. The subcutaneous fat thickness at the upper umbilicus, right side of the umbilicus, and waist in the medical cupping and acupuncture groups were lower than those in the waiting group. The subcutaneous fat thickness at the upper umbilicus and waist in the medical cupping group was lower than that in the acupuncture group. The MetS prevalence in the medical cupping and acupuncture groups was lower than that in the waiting group. Conclusion: medical cupping treatment can effectively alleviate metabolic indices and subcutaneous fat thickness at the abdomen in patients with MetS and abdominal obesity and decrease the MetS prevalence. Its efficacy was better than that of waiting and similar to that of acupuncture. The frequency of medical cupping is lower than that of the acupuncture. Meanwhile, it circumvents some patients’ fear of acupuncture. medical cupping should be clinically promoted.
This review covers the research progress during 2018 for pharmacological studies on traditional medicine and active natural products. The pharmacological reports on traditional medicine against cancers and diabetes were still hot issues.
This annual integrative pharmacology review analyzed the different growth rates and progress of traditional medicine in different diseases, which is able to provide a comprehensive description of the hot spot and development.
A number of researches concerning pharmacology of traditional medicine and active natural products over the past 12 months have outlined the importance of reviewing the progress. This annual integrative pharmacology review evaluates researches published during 2018 in different diseases including cardiovascular and cerebrovascular diseases, cancers, diabetes and metabolic diseases, and so on. The emphasis is on bioactive compounds and extracts from traditional herbs, as well as the novel molecular targets and mechanisms. Moreover, some traditional prescriptions in China and other geographical locations have also been included.
This review summarizes the advances in research on cucurbitacins B, D, E, and I in inducing tumor cell apoptosis, cytoskeletal destruction, cell cycle arrest, and autophagy and in regulating various cancer-related signaling pathways.
Cucurbitacins are present in some traditional Chinese herbs (TCH) such as Gualou (Fructus Trichosanthis),Tianhuafen (Radix Trichosanthis), and Tianguadi (Pedicellus Melo). An ancient book named Shennong Bencao Jing (1602 A.D., Donghan Dynasty of China) has reported that TCH Tianguadi (Pedicellus Melo) and the dried fruit stalk of Cucumis melo L. have been used for treating jaundice because components present in these herbs induce vomiting and aid in expelling phlegm.
Cucurbitacins are highly oxidized tetracyclic triterpenoids that are widely found in plants belonging to Cucurbitaceae family and exert various pharmacological effects. Many cucurbitacin derivatives are available, of which cucurbitacins B, D, E, and I are important members of the cucurbitacin family and exert anticancer effects against various cancers. This review summarizes the advances in research on cucurbitacins B, D, E, and I in inducing tumor cell apoptosis, cytoskeletal destruction, cell cycle arrest, and autophagy and in regulating various cancer-related signaling pathways. In addition, this review summarizes the latest research on the synergistic effects of the combination of cucurbitacins and clinically approved chemotherapeutic drugs. The findings summarized in this review suggest that cucurbitacins are multi-targeting and multi-functional anticancer drugs and that their complex anticancer mechanisms should be examined in future studies. Because of their proven benefits, cucurbitacins have the potential to be used as anticancer drugs in the clinical setting.
Regional ethnic medicine (REM) and traditional Chinese medicine (TCM) have unique experience in the treatment of cancer pain.
There are many different aspects of the treatment of cancer pain in REM and TCM.
TCM and REM are important cancer-assisted treatments in China. Especially for the treatment of cancer pain, TCM and REM are important alternatives.
REM and TCMare both important parts of traditional medicine in China, and they have their own characteristics in the understanding and prevention of diseases. This article compares the understanding, the theoretical prevention and treatment guidance and the clinical application of the REM and TCMon the cancer pain.
Dry cupping therapy can improve the health and overall quality of life of the people by positively influencing their physical and psychological health perceptions.
Cupping therapy was first mentioned in Eber’s papyrus in the ancient Egypt, which is considered an oldest medical book published in 1550 B.C.
Objective: Individuals travel locally and internationally in order to find alternative treatments which are less-toxic and more beneficial to their health and wellness. Despite the popularity of the western system of medicine, cupping therapies are gaining enormous attention in Pakistan as a system of traditional and complementary medicine to ensure the quality of life and wellness notions of the people. The present study aims to examine the effectiveness of dry cupping therapy (DCT) on the health, wellness, and quality of life preferences of health-seeking travelers in a sample of Faisalabad. Methods: DCT was performed for 15 - 20 minutes on subjects by using 3 - 5 disposable cupping glasses. Study participants filled the questionnaires before and after DCT interventions. Partial least square structural equation modeling technique is used in order to statistically analyze the data. Results: A total of 187 subjects participated in two DCT interventions at Coural Wellness Center Faisalabad and provided their final responses after 30 days from 2nd DCT. Respondents’ perceptions of their physical feelings were generally found in a significantly positive and direct relation with DCT and health status (HS), i.e., body pain (β = 0.019), vitality (β = 0.138), and bodily movement (β = 0.207). This trend was observed in the psychological feelings of respondents as well, i.e., emotional feelings (β = 0.169). DCT significantly mediated the overall phenomenon and variance account for values were found between 20% and 80 % for all the study constructs. The scores of all the health and wellness items on the questionnaire were significantly improved in 79.68% of studied participants after 1st and 2nd DCT interventions except for social functioning. Conclusion: Findings of the present study suggest that DCT has an important role in determining the health perceptions and HS of health travelers without potential side-effects. It can improve the health and overall quality of life of the people by positively influencing their physical and psychological health perceptions. It additionally leads to improve travelers’ emotion, behavior, and other daily matters.
Mental disorders are considerate "the evil of the century" by renowned researchers, because a large part of the population in many countries is a diagnosticated, and currently affect youth and children. Among the numerous therapeutic interventions, the music therapy is a non-invasive approach. However, there are very few people who are professionally engaged in research and studies on the subject. Therefore, this article is a literature to talk about the benefits of music therapy sessions for people with stress, depression and anxiety disorders.
This retrospective cohort study showed that long-term traditional Chinese medicine as an adjuvant therapy can improve disease-free survival of postoperative lung cancer patients, especially in patients with stage I and II disease.
This study provided sufficient evidence that long-term traditional Chinese medicine treatment is associated with 5-year disease-free survival in postoperative lung cancer patients, especially in patients with stage I and II disease.
Objective: Traditional Chinese medicine (TCM) has been extensively used as one of popular alternative therapies for several cancers. However, it remains unclear whether TCM treatment is associated with longer survival in lung cancer patients. In this study, we explored the effect of long-term TCM treatment on patients with different stages of lung cancer. Methods: All information of lung cancer patients with stage I-III disease from January 2007 to September 2015 was collected for this retrospective cohort study. Those who were treated with TCM after surgery were divided into TCM group and the others were into the non-TCM group (control group). All patients were regularly followed up by clinic appointment or phone, and all survival data were collected from databases after the last follow-up in October 2017. Results: A total of 575 patients were included in this study, with 299 patients in the TCM group and 276 in the control group. For all patients, 5-year disease-free survival (DFS) was 62.2% in TCM group and 42.1% in the control group, and 6-year DFSs were 51.8% and 35.4%, respectively (HR = 0.51, 95% CI: 0.40 to 0.66, log-rank P ≤ 0.001). For patients with stage I, 5-year DFSs were 83.7% (TCM group) and 57.5% (control group) and 6-year DFSs were 73.7% and 51.9%, respectively (HR = 0.30, 95% CI: 0.18 to 0.50, log-rank P ≤ 0.001). For patients with stage II in the TCM group and the control group, 5-year DFSs were 59.4% and 17.6% and 6-year DFSs were 44.7% and 17.6%, respectively (HR = 0.31, 95% CI: 0.19 to 0.52, log-rank P ≤ 0.001), and for patients with stage III, 5-year and 6-year DFSs in the TCM group were 18.7% and 12.5% compared with 28.4% and 20.3% in the control group (HR = 1.06, 95% CI: 0.72 to 1.56, log-rank P = 0.76). Conclusions: This study demonstrated that long-term TCM treatment as an adjuvant therapy is able to improve the DFS of postoperative stage I-III lung cancer patients, especially in patients with stage I and II disease. However, these observational findings need being validated by large sample randomized controlled trials.
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