Objective: To guide the pregnancy and delivery of patients with abnormal uterus through analyzing the delivery
outcomes of them. Methods: A total of 32 pregnant cases with abnormal uterus were collected in the North China
University of Science and Technology Affiliated Hospital from 2011 to 2018. 7615 cases with normal uterus who
visited the hospital and delivered during the same period were also collected. The rate of abnormal fetal position,
premature rupture of membranes, premature delivery, postpartum complications, and caesarean section, were
compared between the two groups by the χ2 test through SPSS. P values less than 0.05 were considered statistically
significant. Results: There were significant differences in abnormal fetal position, premature rupture of membranes,
premature delivery and spontaneous birth rate between the two groups (P < 0.05), but there was no significant
difference in the incidence of postpartum hemorrhage between the two groups (P > 0.05). In the cause of cesarean
section, there was significant difference in abnormal fetal position and scarred uterus (P < 0.05), but no significant
difference in placenta previa and other causes (P > 0.05). Conclusion: Abnormal fetal position, premature rupture
of membranes and premature delivery are more likely to occur in pregnant women with abnormal uterus than in
normal ones. The rate of cesarean section in patients with abnormal uterus is significantly higher than that of
normal uterus, due to the main reason of abnormal fetal position. Abnormal uterus is a high-risk factor for pregnant
women, and patients with abnormal uterus should be strengthened the management of pregnancy and relaxed the
indications of cesarean section.
As many scientists believe, human aging is a very important part of the program of life-human activity rather than a disease. The human brain may be the controller, performer and participant of the natural program of life-human activity, from birth to death. The program of life-activities of the brain and the human body is very similar to a conventional computer program and it may also be malfunctioning. The work of the natural program of life-activity resembles the work of AI. Each program of life-activity of an individual is repeatedly subjected to natural correction of program tasks in the life of a biophysical being. However, in recent years, scientists from different countries began to seek to reprogram the brain and find the real cause of death. Some biologists and evolutionists believe that this process is nonrandom and that it is controlled by a kind of “death program.” So they call a special set of genes, forcing the body to become decrepit and die, giving way to a new generation of their own kind. The aim of our work is to design new technologies and methods to adjust the life-activity programs from biophysical views, increasing the useful life of bodies by delaying destructive processes and the aging process. Our life-activity program is carried out through the device and IT programs in a mobile application, using contact/contactless frequency code effects on the brain, which is decoded and accepted by the human brain for execution (reprogramming), as a natural addition and an integral part of the brain work. Code programs are compiled according to the working algorithms of the Cosmo-terrestrial structure of life-activity of biophysical objects on the planet Earth. Our technology is one of the varieties of brain-computer technology.
studies have shown that the co-morbidity of insomnia and anxiety and
depression is very prominent, among which 70% of anxiety patients are
accompanied by sleep disorders, which is commonly referred to as
insomnia of liver depression syndrome in traditional Chinese medicine.
The etiology and pathogenesis of traditional Chinese medicine is
liver-qi discomfort, and soothing liver and relieving depression should
be taken as the basic treatment method and treatment principle. By
sorting out the relevant literature on PI3K/Akt signaling pathway, the
relationship between PI3K/Akt signaling pathway and depression and
insomnia was sorted out, and the possible mechanism of Liver-soothing
and Depression-Relieving therapy for insomnia of liver-depression
syndrome was found
This review provides evidences for the recommendation of acupuncture preconditioning at Neiguan (PC6) point in coronary heart disease patients as a non-pharmacological therapeutic method to activate the miR-214/NCX1 pathway.
The concept of acupuncture preconditioning is described in the ancient book of Fan Wang Fang (Eastern Jin Dynasty of China). It refers to the application of acupuncture before the occurrence of disease or when the disease is relatively mild. According to the record of the ancient book of Huang Di Nei Jing (Qin Han Period of China, 475 B.C.-221 B.C.), acupuncture at Neiguan (PC6) point can prevent and treat angina pectoris in coronary heart disease (CHD). The WHO also recommends acupuncture as one of the alternative and complementary therapies for the prevention and treatment of angina pectoris in CHD.
Early reperfusion of ischemic cardiac tissue is usually the best option to improve clinical outcome of angina pectoris, especially of acute myocardial infarction. However, myocardial reperfusion may cause an abnormal increase of intracellular Ca2+-mediated cardiomyocyte death and consequent loss of cardiac function, which is referred to myocardial ischemia/reperfusion (I/R) injury. Recently, the microRNA-214 (miR-214)/Na+/Ca2+ exchanger (NCX) 1 co-expression is a key factor in cellular protection against myocardial apoptosis for myocardial I/R injury. Once activated, miR-214/NCX1 axis can inhibit several Ca2+ downstream signaling effectors that mediate cell death simultaneously. Studies have shown that acupuncture preconditioning has a protective effect on myocardial I/R injury, but its mechanism deserves further research. It has been proved that acupuncture preconditioning for ischemic myocardium successfully inhibit multiple Ca2+ handling related microRNAs that mediate cell death pathways, and miR-214 is one of its targets. In terms of clinical practice, coronary heart disease (CHD) patients benefit a lot from this intervention. However, there is barely no study correlating acupuncture preconditioning to the miR-214/NCX1 co-expression in patients with CHD. This review aims to discuss whether there is some evidence to justify a recommendation of acupuncture preconditioning in CHD patients as a non-pharmacological therapeutic method to activate the miR-214/NCX1 co-expression network model.
As early as 2000 years ago, ancient Chinese medical records had described the relationship between diseases and appearance in detail. Moreover, modern medicine has also constantly studied the relationship between facial features and health in evolutionary terms. It is well known that many hereditary diseases involve certain abnormal facial features and gene mutations. The tumor is also considered as genetic disorder to some extent, so what is the relationship between cancer genetics and congenital development of facial features? Here, we reviewed some clues to the appearance-gene-tumor relation, which might become the targets in the early prevention or gene therapy of cancer in the future. This summary provided us a new strategy for the cancer genetic screening and a new research direction for genetic diagnosis of the potential disease.
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