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有毒虫类中药在结直肠癌临床治疗中的运用 
伍谨林, 杨柱, 龙奉玺, 刘薰, 王佳, 余婷, 唐东昕
经典中医研究    2019, 2 (3): 44-48.   https://doi.org/10.12032/CCMR20190301
Abstract PDF (1243KB)  
收集历代中医论著文献,用“以毒攻毒”作为有毒虫类中药治疗结直肠癌的中医理论基础, 搜寻古今方药中运用有毒虫类药物治疗结直肠癌实例,以及结合有毒虫类中药治疗结直肠癌的 现代运用,并提出应正确掌握药物使用原则、可能产生的不良反应、炮制方法及有效剂量等有 毒虫类中药的使用注意事项。 
吴雄志教授扶阳思想探析
邓振鈺, 王栋
经典中医研究    2019, 2 (4): 73-77.   https://doi.org/10.12032/CCMR20190402
Abstract PDF (779KB)  
本文旨在总结吴雄志教授的扶阳思想以期更好地指导临床。本文作者通过整理吴老师授课内容以及查阅相关书籍和文献获取有效信息,总结吴雄志教授扶阳思想。吴雄志教授扶阳思想博大精深,理法方药完备,其验方八味回阳饮验之临床疗效卓著,其理论皆源于临床并能有效指导临床实践,值得深入探索学习。
温阳散寒法治疗乳腺癌浅析
栾鑫源, 杨雪
经典中医研究    2019, 2 (4): 82-88.   https://doi.org/10.12032/CCMR20190404
Abstract PDF (914KB)  
乳腺癌中医称为“乳岩”,是女性最常见的恶性肿瘤之一。包括手术、放化疗、内分泌治疗、 靶向治疗、免疫治疗等在内的综合治疗已成为乳腺癌治疗的主要方法。中医药治疗恶性肿瘤已 有 2000 多年的历史,其在乳腺癌综合治疗中具有不可替代的作用。中医治疗乳腺癌的常用治法 包括补益脾胃、滋补肝肾、疏肝理气、解毒散结。但我们认为阳虚寒凝是乳腺癌的关键病机, 温阳散寒法是乳腺癌的基本治法。本文浅述了温阳散寒法治疗乳腺癌的理论依据及现代基础、 临床研究,为临床应用温阳散寒法治疗乳腺癌提供依据。 
扶阳理论中西汇通浅谈 
李晓阳
经典中医研究    2019, 2 (4): 89-92.   https://doi.org/10.12032/CCMR20190406
Abstract PDF (644KB)  
本文对扶阳理论体系“阳”的内涵外延进行探讨,试图明确扶阳的中医对象,以分析扶阳学术思想理论根基的合理性。继而以中西汇通思路入手,分析扶阳的现在医学内涵与机理,提出扶阳是以调节下丘脑—垂体—肾上腺轴等内分泌系统平衡为基础,继而调节自主神经系统功能,改变人体失衡代谢功能紊乱,从而恢复人体健康状态的理论解读。
抓独法在中医妇科中的应用刍议
沈佳
经典中医研究    2020, 3 (1): 1-8.   https://doi.org/10.12032/CCMR20200101
Abstract PDF (931KB)  
本文介绍了作为六经模型运用五法之一的抓独法的概念、源流,以及与经方派抓主证的区别。还介绍抓独法有抓证法、抓枢法与抓病法三种方法,并指出四诊均可抓独。最后,从经典到临床介绍抓独法在中医妇科中的应用范例及体会。
Bio-characteristic profiling related to clinic: A new technology platform for quality evaluation of Chinese materia medic
Li-Na Wen, Ai-Ting Wang, Na Guo, Yumei Han, Can Yan, Dan Yan
6TMR Modern Herbal Medicine    2019, 2 (4): 215-224.   https://doi.org/10.12032/TMRmhm2017B54
Abstract PDF (859KB)  
Quality evaluation is a bottleneck restricting the modernization and internationalization of Chinese materia medica (CMM). Due to characteristics of multi-component, multi-efficacy, multi-target, the existing quality evaluation system still cannot fully meet quality control needs of CMM. Hence, the author put forward “Bio-characteristic profiling related to clinic, BPRC” academic concept, meanwhile, fully take the advantage of analysis method with clinical monitoring superiority or profiling characteristics, build up "BPRC" new technology platform, in order to realize “real-time, dynamic and full-range monitoring” new technologies of CMM quality evaluation system and promote the further development of CMM industry.
Similarity measurement of Chinese medicine ingredients for cold-hot nature identification
Guo-Hui Wei, Xian-Jun Fu, Zhen-Guo Wang
6TMR Modern Herbal Medicine    2019, 2 (4): 183-191.   https://doi.org/10.12032/TMRmhm2017A58
Abstract PDF (478KB)  
Objective: Nature theory of Chinese medicine (CM) is the core basic theory of Traditional Chinese Medicine (TCM), in which cold-hot nature is the focus of research. Studies have found that CM ingredients are the material basis for the production of medicine natures. Therefore, it is speculated that CMs with similar composition of substances should have similar medicinal nature. Modern work studies cold-hot medicine of CMs with chemical fingerprinting technology because the chemical fingerprint data of CM can reflect the whole composition of CM ingredients. Methods: To verify the hypothesis above, in this work, we study quantifying the similarity of CM ingredients to fingerprint similarity, and explore the relationship between the composition of CMs and cold-hot nature. Firstly, we utilize ultraviolet (UV) spectrum technology to analyze 61 CMs, which have clear cold-hot nature (including 30 ‘cold’ CMs and 31 ‘hot’ CMs). Secondly, with the constructed fingerprint database of CMs, a distance metric learning algorithm is studied to metric the similarity of UV fingerprints. Finally, a retrieval scheme is proposed to build a predictive identification model to identify cold-hot nature of CMs. Results: By means of numerous experiment analyses, ultraviolet spectrum data of petroleum ether solvent can better represent CMs to distinguish between cold and hot natures. Comparing with existing classical models, the proposed identification scheme has better predictive performance. Conclusion: The experimental results prove our inference that CMs with similar composition of substances should have similar medicinal nature. The proposed prediction model is proved to be effective and feasible.
Clinical analysis of the delivery outcomes of women with abnormal uterus
Jin-Fang Hu, Yan-Fang He, Jun Xin
5TMR Clinical Research    2019, 2 (4): 165-170.   https://doi.org/10.12032/TMRClinRes20191012016
Abstract PDF (203KB)  

Objective: To guide the pregnancy and delivery of patients with abnormal uterus through analyzing the delivery outcomes of them. Methods: A total of 32 pregnant cases with abnormal uterus were collected in the North China University of Science and Technology Affiliated Hospital from 2011 to 2018. 7615 cases with normal uterus who visited the hospital and delivered during the same period were also collected. The rate of abnormal fetal position, premature rupture of membranes, premature delivery, postpartum complications, and caesarean section, were compared between the two groups by the χ2 test through SPSS. P values less than 0.05 were considered statistically significant. Results: There were significant differences in abnormal fetal position, premature rupture of membranes, premature delivery and spontaneous birth rate between the two groups (P < 0.05), but there was no significant difference in the incidence of postpartum hemorrhage between the two groups (P > 0.05). In the cause of cesarean section, there was significant difference in abnormal fetal position and scarred uterus (P < 0.05), but no significant difference in placenta previa and other causes (P > 0.05). Conclusion: Abnormal fetal position, premature rupture of membranes and premature delivery are more likely to occur in pregnant women with abnormal uterus than in normal ones. The rate of cesarean section in patients with abnormal uterus is significantly higher than that of normal uterus, due to the main reason of abnormal fetal position. Abnormal uterus is a high-risk factor for pregnant women, and patients with abnormal uterus should be strengthened the management of pregnancy and relaxed the indications of cesarean section.

Anti-aging theory of quantum nature and brain reprogramming
Yurii Pozniak
90Life Research    2019, 2 (3): 113-118.   https://doi.org/10.12032/life2019-0725-401
Abstract HTML PDF (2093KB)  

As many scientists believe, human aging is a very important part of the program of life-human activity rather than a disease. The human brain may be the controller, performer and participant of the natural program of life-human activity, from birth to death. The program of life-activities of the brain and the human body is very similar to a conventional computer program and it may also be malfunctioning. The work of the natural program of life-activity resembles the work of AI. Each program of life-activity of an individual is repeatedly subjected to natural correction of program tasks in the life of a biophysical being. However, in recent years, scientists from different countries began to seek to reprogram the brain and find the real cause of death. Some biologists and evolutionists believe that this process is nonrandom and that it is controlled by a kind of “death program.” So they call a special set of genes, forcing the body to become decrepit and die, giving way to a new generation of their own kind. The aim of our work is to design new technologies and methods to adjust the life-activity programs from biophysical views, increasing the useful life of bodies by delaying destructive processes and the aging process. Our life-activity program is carried out through the device and IT programs in a mobile application, using contact/contactless frequency code effects on the brain, which is decoded and accepted by the human brain for execution (reprogramming), as a natural addition and an integral part of the brain work. Code programs are compiled according to the working algorithms of the Cosmo-terrestrial structure of life-activity of biophysical objects on the planet Earth. Our technology is one of the varieties of brain-computer technology.

Analysis of the Relationship between PI3K/Akt Signaling Pathway and Insomnia of Liver Depression Syndrome
Yun-Qiao Wang, Meng Xia, Xiao Jiang
Precision Medicine Research    2019, 1 (2): 32-36.   https://doi.org/10.12032/PMR201900006
Abstract PDF (225KB)  

Some studies have shown that the co-morbidity of insomnia and anxiety and depression is very prominent, among which 70% of anxiety patients are accompanied by sleep disorders, which is commonly referred to as insomnia of liver depression syndrome in traditional Chinese medicine. The etiology and pathogenesis of traditional Chinese medicine is liver-qi discomfort, and soothing liver and relieving depression should be taken as the basic treatment method and treatment principle. By sorting out the relevant literature on PI3K/Akt signaling pathway, the relationship between PI3K/Akt signaling pathway and depression and insomnia was sorted out, and the possible mechanism of Liver-soothing and Depression-Relieving therapy for insomnia of liver-depression syndrome was found

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