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Evaluation of scientific evidence for abortifacient medicinal plants mentioned in traditional Persian medicine
Ensiye aafi, Malihe Tabarrai, Mehran Mirabzadeh Ardakani, Mohammad Reza Shams Ardakani, Seyede Nargess Sadati Lamardi
1Traditional Medicine Research    https://doi.org/10.12032/TMR20200106150
温阳散寒法治疗乳腺癌浅析
栾鑫源, 杨雪
经典中医研究    2019, 2 (4): 82-88.   https://doi.org/10.12032/CCMR20190404
Abstract PDF (914KB)  
乳腺癌中医称为“乳岩”,是女性最常见的恶性肿瘤之一。包括手术、放化疗、内分泌治疗、 靶向治疗、免疫治疗等在内的综合治疗已成为乳腺癌治疗的主要方法。中医药治疗恶性肿瘤已 有 2000 多年的历史,其在乳腺癌综合治疗中具有不可替代的作用。中医治疗乳腺癌的常用治法 包括补益脾胃、滋补肝肾、疏肝理气、解毒散结。但我们认为阳虚寒凝是乳腺癌的关键病机, 温阳散寒法是乳腺癌的基本治法。本文浅述了温阳散寒法治疗乳腺癌的理论依据及现代基础、 临床研究,为临床应用温阳散寒法治疗乳腺癌提供依据。 
加味寿胎丸治疗妊娠子宫肌瘤红色变性1例
孙成力, 张超
经典中医研究    2020, 3 (1): 13-17.   https://doi.org/10.12032/CCMR20200103
Abstract PDF (829KB)  
子宫肌瘤红色变性多见于妊娠期,是一种特殊类型的坏死。妊娠期肌瘤红色变性时,临床上可有剧烈腹痛,或伴恶心呕吐、发热、血白细胞计数升高等表现。治疗方面除使用宫缩抑制剂之外,无特殊治疗及止痛的有效药。中药对治疗妊娠合并子宫肌瘤红色变性所引起的疼痛有独到之处,在吴门验方加味寿胎丸保胎基础上运用当归芍药散等随证加减有较好疗效。现报道1例中药治疗本病的案例供参考。
抓独法在中医妇科中的应用刍议
沈佳
经典中医研究    2020, 3 (1): 1-8.   https://doi.org/10.12032/CCMR20200101
Abstract PDF (931KB)  
本文介绍了作为六经模型运用五法之一的抓独法的概念、源流,以及与经方派抓主证的区别。还介绍抓独法有抓证法、抓枢法与抓病法三种方法,并指出四诊均可抓独。最后,从经典到临床介绍抓独法在中医妇科中的应用范例及体会。
浅析吴门验方缩经汤的临床应用
孙迎春
经典中医研究    2020, 3 (1): 18-22.   https://doi.org/10.12032/CCMR20200104
Abstract PDF (715KB)  
本文着重介绍吴门验方缩经汤的临床应用。本方是针对子宫内膜异常问题的专方。笔者学习吴雄志教授使用缩经汤的理论和医案,结合自己临床经验,从方药解析、合方加减、验案举隅等方面展开论述,简要阐明缩经汤的方义和加减变化,从而为诊治本病拓宽思路,提高疗效。
丁丽仙教授治疗排卵期出血验案举隅
王楚函, 丁丽仙
经典中医研究    2020, 3 (1): 9-12.   https://doi.org/10.12032/CCMR20200102
Abstract PDF (699KB)  
排卵期出血属于排卵性异常子宫出血的范畴,有研究表明其发病率约17%。排卵期出血不仅导致生殖系统疾病,还影响身心健康。文中主要介绍丁氏妇科第十代传人,名中医丁丽仙教授对排卵期出血病因病机的认识和灵活运用丁氏妇科滋阴清热止血方治疗排卵期出血取得显著疗效的经验。
针刺联合中药治疗绝经综合征医案三则体会
周曙光
经典中医研究    2019, 2 (3): 53-57.   https://doi.org/10.12032/CCMR20190303
Abstract PDF (834KB)  
绝经综合征是女性常见病、多发病,患者痛苦大,治疗意愿强烈。现代医学对此病发病机制认识清晰,治疗方法明确,但药物治疗副作用明显,患者服药依从性低。传统医学对此病的认识过于宏观,致使用药用方不够精准,临床疗效不突出。本文试图运用中西汇通的思想,结合现代中药药理研究成果、古今文献记载有效方剂、现代针灸效应机制研究等,用于临床,效果显著。现对三则代表性医案进行回顾总结。
Systematic evaluation of Kang-ai injection combined with chemotherapy versus chemotherapy alone in the treatment of ovarian cancer
Meng-Xi Gao, Ai-Ying Zhang, Tian-Tian Gai, Wei Fan, Yan Wang
7Drug Combination Therapy    2019, 1 (1): 19-30.   https://doi.org/10.12032/DCT201901004
Abstract PDF (680KB)  

Objective: This study was conducted to evaluate the clinical efficacy and safety of Kang-ai injection combined with chemotherapy in the treatment of ovarian cancer. Methods: the databases of VIP, CNKI, WanFang, CBM, Pub Med, Cochrane Library and EMBASE were searched to collect the randomized controlled trials (RCTs) of Kang-ai injection, combined with chemotherapy versus chemotherapy alone for the treatment of ovarian cancer. The retrieval time was from the database setup to December 20, 2018. After two researchers independently screened the researches, extracted data and evaluated the risk of the included studies, the RevMan 5.3 software was used for analysis. A total of 8 RCTS were included. Results: Results showed that patients in Kang-ai injection combined with chemotherapy group were superior to the conventional chemotherapy group patients in total effective rate [RR = 1.31, 95% CI (1.11, 1.54), P = 0.001], quality of life [RR = 1.69, 95% CI (1.35, 2.13), P < 0.001], leukopenia [RR = 0.63, 95% CI (0.51, 0.77), P < 0.001], nausea and vomiting [RR = 0.41, 95% CI (0.24, 0.70), P = 0.001], decreased hemoglobin [RR = 0.50, 95% CI (0.28, 0.88), P = 0.002], and thrombocytopenia [RR = 0.45, 95% CI (0.24, 0.85), P = 0.01]. Conclusion: Kang-ai injection combined with chemotherapy for ovarian cancer is better than chemotherapy alone in improving total effective rate and quality of life, reducing the incidence of adverse reactions. Limited by the number and quality of included studies, the above conclusions are yet to be verified by more high-quality studies.

Analysis on the medication rules and mechanisms of action of traditional Chinese medicine in treating cervical cancer
Ying Chen, Yao Yang, Xin-Zhe Zhao, Guo-Wei Zhang
7Drug Combination Therapy    2019, 1 (3): 173-185.   https://doi.org/10.12032/DCT201903001
Abstract PDF (1163KB)  

Objective: To summarize the rule of application of traditional Chinese medicine (TCM) in the prevention and treatment of cervical cancer, and to explore the molecular mechanism of the compatibility of core herbs. Methods: Collect relevant literatures on cervical cancer in Chinese National Knowledgey Ifrastructure (CNKI), use TCM inheritance platform system (TCMISSV2.5) for association rules and complex system entropy clustering analysis; use BATMAN-TCM online analysis tools to construct target-pathway-disease network to reveal the underlying mechanisms of action. Results: Among the 78 prescriptions selected, a total of 172 Chinese medicines were used, and the five most frequently used herbs were Huang-bo (Phellodendri Chinrnsis Cortex), Fu-ling (Poria Cocos), Huang-qi (Hedysarum Multijugum Maxim.), Bai-hua-she-she-cao (Hedyotis Diffusae
Herba
) and Gan-cao (Licorice). Bai-hua-she-she-cao (Hedyotis Diffusae Herba) and Huang-qi (Hedysarum Multijugum Maxim.), Bai-hua-she-she-cao (Hedyotis Diffusae Herba) and Fu-ling (Poria Cocos), Bai-zhu (Atractylodes Macrocephala Koidz.) and Fu-ling (Poria Cocos) are the three most commonly used medicine match. In addition, through cluster analysis, a total of 4 core herbs ompatibility and 2 new prescriptions were excavated. Herbs in the new prescriptions which are used to clearing heat-toxin and removing dampness were most frequently used. Through the analysis of
the signal pathway of high frequency Chinese medicines, we found that neuroactive ligand-receptor interaction pathway may play important roles.
Conclusion: The core Chinese medicines for the prevention and treatment of cervical cancer are mainly clearing heat-toxin and removing dampness.
The core Chinese medicines may play their anti-cervical cancer by interfering with the neuroactive ligand-receptor interaction signaling pathway.

陈慧侬教授膜样痛经治验一例
李文意, 何雪婷, 陈爱妮, 陈慧侬
经典中医研究    2019, 2 (1): 11-13.   https://doi.org/10.12032/CCMR20190103
Abstract PDF (1355KB)  
陈慧侬教授是我国中医妇科名老中医,在治疗痛经方面积累了丰富经验。陈老认为膜样痛经多为肾虚血瘀所致,临床上运用补肾活血法治疗效果甚佳。
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