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Ritual Treatment of Shamans in Northeast China
Xin-Hua Zhao
92Psychosomatic Medicine Research    2020, 2 (1): 25-29.   https://doi.org/10.12032/psmr2020-0320-020
Abstract PDF (421KB)  
Shaman originates from the Tungusic-Ian language. In northeast China, the Shamanism traditions have gradually merged, and formed a compound belief form of polytheism and immortality. When a Shaman enters a special state, he has special abilities beyond ordinary people, such as divination, healing, and disaster relief. The most important thing is that as a messenger of communication between man and God, the Shaman expresses his wishes to God. Man communicates the will of God. The Shaman relies on the drum dance and sings the divine music, through the Shaman ritual to convey the request of people and the will of God. This article summarizes the Shaman's ritual therapy methods (music therapy and dance therapy) and psychological mechanism research, and provides a reference for ritual therapy.
Complementary and alternative medicine in European countries - legislative framework
Jovana Milenkovic, Sergey Bolevich, Gvozden Rosic
1Traditional Medicine Research    https://doi.org/10.12032/TMR20190718125
Complementary and alternative medicine applications in cancer medicine
Milena Jurisevic, Sergey Bolevich
1Traditional Medicine Research    2020, 5 (1): 7-21.   https://doi.org/10.12032/TMR20190728127
Abstract HTML PDF (443KB)  

Highlights

(1) The use of complementary and alternative medicine (CAM) is growing rapidly especially among younger female patients with cancer with higher education.

(2) Most patients with cancer consider CAM as a harmless option in their healing process, which is not always the case.

(3) Clinical-based evidence for mind-body therapies has been established, and this type of CAM can be recommended for patients with cancer during chemotherapy.

Traditionality

The use of complementary and alternative medicine (CAM) plays an important role in the prevention and treatment of diseases since the ancient times. In the 16th-11th century B.C.E., there were earliest notes of tumors and their treatment methods were described by traditional Chinese practitioners. It has been known that herbal medicine are used in Egypt and in traditional Chinese medicine since 4500 B.C.E. Since the early 1970s, the use of CAM in cancer treatment has expanded worldwide. Numerous studies point to the benefits of Ayurveda yoga in patients with cancer, improving quality of life. China acupuncture has been shown beneficial in controlling vomiting and pain in patients with cancer. Reflexology, which was practiced for years by followers of Chinese, Egyptian, and Indian medicine, has been successfully used to relieve pain in patients with cancer. Mushroom Agaricus blazei has been mostly used in Japan but is currently in the first phase of the clinical trial in patients with cancer.

Abstract

Besides conventional medicine, many patients with cancer seek complementary and alternative medicine (CAM) as an additional treatment option. Since the early 1970s, the use of CAM in cancer treatment has expanded worldwide. CAM, as a tempting option, was used by patients with cancer mainly due to easy accessibility. Patients with cancer used CAM to achieve better quality of life or to find a cure. As physicians are mainly unaware of CAM use by patients, doctor-patient communication about CAM use should be brought to a higher level. To identify circumstances in which CAM are preferred, further investigations are needed especially in biologically based therapies. Clinical-based evidence for mind-body therapies have been established, so this type of CAM can be recommended for patients with cancer during chemotherapy. Future studies are necessary to fill the gaps so that CAM users, as well as medical experts, are in position to clearly determine all the benefits and disadvantages of the mentioned therapy.

Computation of drug efficacy indices Q(VPK) of certain common formulations (Curnas) used in Siddha system of medicine
Abhilash Mullasseril
2TMR Integrative Medicine    2019, 3: e19021.   https://doi.org/10.12032/TMRIM201903021
Abstract PDF (340KB)  

The Siddha system of medicine is one of the ancient systems of the world that is believed to be originated and found popular in the southern parts of India. The philosophical bases of this alternative system are also found comparable with the Ayurveda. The process of computing the Drug Efficacy Index Q(VPK) of various Ayurvedic formulations was reported earlier and supported by many research publications. In this modern era of medicine, the incorporation of artificial intelligence to various research fields is found common. In this paper, it is tried to incorporate artificial intelligence to predict the efficacy of certain unique powder formulations of the Siddha System of medicine that are frequently prescribed in the common parlance. We computes the Drug Efficacy Indices Q(VPK) of certain common simple curnas of Siddha System of Medicine, such as Amukkara kizzhangu Curnam, Arathai Curnam, Nannari Curnam, Nellivattral Curnam and Punaikali Curnam, using a previously reported method which was found successful for the computation of efficacies of various Ayurvedic formulations. The possible variations in the efficacies of these powder formulations with respective recommended adjuvants used in common parlance were also studied from the computed values and compared accordingly. The selected curnas are unique and common but simple/single powder formulations for the practice of Siddha system of medicine.

A darkfield microscopic evaluation of the live blood effects caused by Moringa oleifera
Howard W. Fisher, Colombe Gauvin
90Life Research    2019, 2 (3): 87-92.   https://doi.org/10.12032/life2019-0725-002
Abstract HTML PDF (5462KB)  

Erythrocyte aggregation is the tendency of erythrocytes to form aggregates whose shapes change according to normal variations or pathological conditions. Consequently, regardless of cause, these anomalies effect changes to flow dynamics and predispose the inability to carry out transportation activities and decrease functional capillary density or decrease erythrocyte surface area, also decreasing functional efficiency. Functional capillary density is the determination of the number of capillaries in an area that have erythrocyte flow and relates to the subsequent ability of the blood to deliver nutrients, fluid and solute exchange, and waste product excretion. Red blood cell aggregation has a significant impact on functional capillary density. Moringa oleifera, one of the most phytonutrient dense plants as identified by the NIH, has garnered interest by those involved with anti-aging medicine. The US National Institutes of Health, the nation’s medical research agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce the burdens of illness and disability, has affirmed Moringa oleifera can “arrest, reverse, and cure, over 300 different diseases and disorders.” Regular use of Moringa oleifera has been shown to have a multitude of health benefits. In addition to this, Moringa oleifera provides all of the essential amino acids, vital vitamins, contains several important minerals, is an incredibly powerful antioxidant, is high in fiber, stimulates the immune system to fight cancerous cells, tumours, ulcers, epileptic seizures and cleanses and detoxifies the entire body. Moringa oleifera has been shown to protect platelets against aggregation. In this investigation, live blood microscopic evaluation indicates positive changes in the shape and spatial orientation of the erythrocytes and decreased incidence of aggregation and rouleaux indicating improved functional capillary density. In conclusion, a proprietary formula of raw organic Moringa oleifera has empirically demonstrated subjective beneficial changes in patients who have supplemented with this formula.

A summary of the pharmacologically tested aphrodisiac plants for sexual dysfunction
Marko Mornar Jelavic, Hrvoje Pintaric
90Life Research    2019, 2 (3): 93-98.   https://doi.org/10.12032/life2019-0725-301
Abstract HTML PDF (1003KB)  

Sexual dysfunction is a disruption of normal sexual intercourse and may be a consequence of various organic and psychological disorders. It is the most frequent at patients with cardiovascular and neurological diseases sedentary lifestyle arterial hypertension diabetes obesity and metabolic syndrome and may disrupt their emotional life. But sexual dysfunction may occur simply because of the physical aging of the body. Physiologic changes that occur with aging will affect sexual function and could be exacerbated by the above-mentioned diseases. Except for the sexual counseling and standard medications (phosphodiesterase type 5 (PDE5) - inhibitors local estrogen therapy) some of the herbal medicines (aphrodisiacs) may be helpful in the treatment of these patients making them emotionally younger and happier. In this review we bring a list of the pharmacologically tested aphrodisiac plants. But we have a lack of information about their mechanisms of action drug interaction and safety profile. Until the relevant information is collected uses of these products may be risky to the human being and should be prescribed only in consultation with a specialist. Sexual dysfunction is a disruption of normal sexual intercourse and may be a consequence of various organic and psychological disorders. It is the most frequent at patients with cardiovascular and neurological diseases sedentary lifestyle arterial hypertension diabetes obesity and metabolic syndrome and may disrupt their emotional life. But sexual dysfunction may occur simply because of the physical aging of the body. Physiologic changes that occur with aging will affect sexual function and could be exacerbated by the above-mentioned diseases. Except for the sexual counseling and standard medications (phosphodiesterase type 5 (PDE5) - inhibitors local estrogen therapy) some of the herbal medicines (aphrodisiacs) may be helpful in the treatment of these patients making them emotionally younger and happier. In this review we bring a list of the pharmacologically tested aphrodisiac plants. But we have a lack of information about their mechanisms of action drug interaction and safety profile. Until the relevant information is collected uses of these products may be risky to the human being and should be prescribed only in consultation with a specialist.

A foreword from the Editor-in-Chief
Chang-Gang Sun
TMR Theory and Hypothesis    2018, 1 (1): 1-1.   https://doi.org/10.12032/TMRTH201801001
Abstract PDF (159KB)  

The traditional Chinese medicine (TCM) is an effective and precious medical heritage shown by the history. It has formed unique and complete theoretical system in prevention and treatment for disease. Many ancient medical literatures recorded the massive medical theories and abundant medical experience and was expressed with the distinct characteristics of ancient Chinese.Up to now, TCM still retains its new vitality in clinical practice, and participates in the maintenance of human health in its unique way. However, the inherent national culture attribute and language of TCM restrict its internationalization cognition, communication and dissemination. But the value of TCM will not vanish because of the development of modern science and technology. On the contrary, with the renewal and reform of the theoretical system of modern medical methods, traditional medical research is endowed with a new significance of the times, and the value of traditional medicine has been excavated and elucidated to a greater extent.

Tumor: Life Retrogression?
Xiong-Zhi Wu, Hao-Ran Zhang
4TMR Theory and Hypothesis    2018, 1 (1): 2-8.   https://doi.org/10.12032/TMRTH201801002
Abstract PDF (270KB)  
Cancer emerged in human history for centuries. It seems that while human beings are evolving, tumors are always on their heels. In order to explain and study the mechanism of tumor progression, we proposed a new hypothesis that the tumor is a retrogression of life evolution, in other word, a resurgence of some past fragments in human development history. Our inference was based on the fact that tumors are not foreign diseases, but use of human inherent developmental genes to achieve self-improvement. Characteristics and biological behavior of tumor cells are similar to human normal stem cell to some degree. Thus, studying the process of human evolution could speculate and analyze the occurrence and development of tumors. The latest research showed that many cancer treatment were also taking advantages of those features about retrogression. Continuous in-depth analysis about tumor environmental characteristics and internal law of human evolution may produce new approaches to promote cancer prevention and treatment. Our hypothesis, for the first time, proposed that taking advantage of the evolution laws to reverse the tumor progression as a path of life retrogression is better than exterminating them completely as outside enemies. Some new studies on tumor induced differentiation had also demonstrated the clinical significance of our hypothesis
Construction of traditional Chinese medicine culture and characteristic community culture : a review
Jia- Jia Zhou, Wen-Wen Zhao, Hui-Xing Ding, Chun-Hua Zhang, Pei-Yao Li, Chun-Guang Yu
4TMR Theory and Hypothesis    2018, 1 (1): 9-12.   https://doi.org/10.12032/TMRTH201801003
Abstract PDF (183KB)  
The broad and profound Chinese medicine culture is an important part of Chinese traditional culture, which nourishes the vigorous development of modern Chinese medicine. At present, traditional Chinese medicine (TCM) culture faces challenges and opportunities. As the inheritor of Chinese medicine culture,we bear the burden of inheriting and carrying forward TCM culture. Distinctive community culture is mainly playing value guidance and education transmission function in the process of residents identifying with the culture of Chinese medicine. Therefore, building a distinctive community culture under the guidance of the essence of TCM can effectively inherit and develop TCM culture. 
Analysis of Mechanism of Indigo Naturalis in Treating Chronic Myelocytic Leukemia Based on Two-dimentional Model of Protein-protein Interaction Network-molecular Docking Technique
Xiao-Ming Zhang, Li-Juan Liu, Chao Zhou, Jing Zhuang, Hong Liu, Jing Zhuang
4TMR Theory and Hypothesis    2018, 1 (1): 13-17.   https://doi.org/10.12032/TMRTH201801004
Abstract PDF (570KB)  
To explore the molecular mechanism of Indigo Naturalis in intervening chronic myelocytic leukemia (CML) under the guidance of protein-protein interaction network, the molecular docking technique and in vitro cell experiment were chosen. CML-related genes were obtained from the online mendelian inheritance in man database (OMIM), then String 10. 0 was used for text mining and constructing the CML protein-protein interaction network. The interaction data were input in Cytoscape 3. 4. 0 software, plug-in CentiScaPe 2. 1 was used for implement topology analysis. Small active substances of Indigo Naturalis were obtained from a third-party database, which were optimized by Chemoffice 8. 0 and Sybyl 8. 1, then small molecular ligand library was obtained. The molecular docking was carried out by Surflex-Dock module, the key target was received after scoring. Protein-protein interaction network of CML was constructed, which was consisted of 425 nodes ( proteins) and 2 799 sides ( interactions). The key gene JAK2 was got. CML is a polygenic disease and JAK2 is likely to be a key node. 
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