Editors-in-Chief: CG Sun PhD, Prof.
ISSN 2538-130X
4TMR Theory and Hypothesis is a peer-reviewed quarterly journal sponsored by TMR publishing group. It has been included in ScienceOpen and Google Scholar. The journal primarily aims to include innovative papers that combine these two theories with modern biomedicine, physics, chemistry and mathematic models. Hypotheses, basic and clinical researches, literature review and analysis which are carried out on a certain theory, phenomenon and development process of traditional Chinese medicine, and paper that reported the influence of traditional medicine on politics, economy, and culture can also be included. ... More

Current Issue     20 June 2019, Volume 2 Issue 2 Previous Issue   
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Integrative thinking facilitates traditional medical research
Zhi-ping Yang
4TMR Theory and Hypothesis. 2019, 2 (2): 164-165.  
Abstract ( 116 )     PDF (175KB) ( 24 )  
Concept of dushi visha (latent poison) a review in ayurveda
Dr.Deepti Patel, Dr.S.R.Inchulkar, Dr.YuvrajKaushik, Dr.N.S.Chauhan
4TMR Theory and Hypothesis. 2019, 2 (2): 166-172.   https://doi.org/10.12032/TMRTH201902001
Abstract ( 91 )     PDF (903KB) ( 20 )  
A poison, which is having fewer properties, which means less thanit’s own ten classical properties
or the poison which is having lesser potency of all ten properties, attains a accumulative or hidden
stage in the body is called Dushi Visha (latent poison). Low potency of all the ten qualities of
poison are said to be responsible for the delayed action and cumulative toxicity on the body. A
much detailed description about DushiVisha is not seen in Ayurvedic classics. The concept of
DushiVisha is still an enigma. To understand Dushi Visha, it is important to understand that what
are theoriginating factors can be considered under DushiVisha, how it remains in the body without
undergoing elimination, how does it causes cumulative toxicity, which factors will aggravate
DushiVisha, how the clinical features of DushiVisha will be presented in the body. To get proper
answer to all these practical queries, it is necessary to go through it’spathology. Here an attempt is
made to review the concept of DushiVisha in detail.
The importance and clinical significance of the development of Miao Medicine PRO scale
Xian-man Wei, Zhu Yang, Feng-xi Long, Wen-yu Wu, Hui-li Shui, Dong-xin Tang,
4TMR Theory and Hypothesis. 2019, 2 (2): 173-178.   https://doi.org/10.12032/TMRTH201902002
Abstract ( 77 )     PDF (891KB) ( 20 )  
As an important part of national medicine, Miao medicine has established a unique theoretical
system in its process of continuous development and improvement. Through clinical practice and
application, it has been proven to have natural and therapeutic effects. It has the advantages of wide
application range, authentic medicinal materials and easy price acceptance.With more attention paid
to the Patient's subjective feeling, Patient Reported Outcome from the standpoint of patients, this
advanced and scientific method of clinical efficacy evaluation takes the feelings directly transmitted
by patients as the "index" to evaluate the clinical efficacy, so as to guide the clinical plan, improve
the medical quality and improve the therapeutic effect and clinical outcome. Therefore, summarizing
and studying the models of Patient Reported Outcome scales at home and abroad, and developing
the Patient Reported Outcome scale unique to Miao Medicine, is of great significance for us to
guide and improve the clinical treatment of the motherland medicine.
The new idea of children with tic syndrome: regulating the five Zang-organs with spleen and stomach system as the center
Kai Zhang
4TMR Theory and Hypothesis. 2019, 2 (2): 179-184.   https://doi.org/10.12032/TMRTH201902003
Abstract ( 60 )     PDF (383KB) ( 13 )  
The pediatric body of pure yang, the liver is often more than enough, the spleen is often insufficient,
Yang moving surplus, and Yin essence is insufficient, at the same time, children are the body of
immature yin and yang, prone to imbalance of yin and Yang, so deficiency of phlegm accumulation
and endogenous liver wind, feel ill at ease, dysfunction of lung qi, Insufficiency of kidney yin are
the fundamental pathogenesis of children with tic syndrome. This article discusses the relationship
between children with tic syndrome and the five Zang-organs, and how to regulate the viscera
through regulating the spleen and stomach system, treating both manifestation and root cause of
disease, and put forward a new treatment that the spleen and stomach system should be taken as the
center to regulate the five Zang-organs in children with tic syndrome, which should be resolved in
order of importance and urgency and treated in stages.
Poison as a treatment with special reference to Ayurveda
4TMR Theory and Hypothesis. 2019, 2 (2): 185-188.   https://doi.org/10.12032/TMRTH201902004
Abstract ( 78 )     PDF (239KB) ( 23 )  
Visha (POISON) are the substances which when administered prove fatal either sooner or later.
This fatality is due to the qualities of visha that are exactly opposite to the nature of oja which is the
vital component of life and causes destruction of life. Though they are previewed as visha, the same
qualities can be utilized in the treat-ment after proper shodhana, which alters basic toxic properties
like vyavaayi, vikasi, sookshma and yogavahi. Thus many visha are used in the formulations in
order to increase the potency, bioavailability, therapeutic values. Hence Ayurveda highlights that
when visha is utilized in a proper way can become the best medicine. Though basically they are
visha, when properly administered along with pathyas they act as vishaghna, rasayana in many
conditions.The present paper discusses about use of vi-sha in the making of formulations which are
indicated in the untreated, chronic, auto immune diseases and also in acute management
Professor Xudong Tang's experience in the treatment of gastroesophageal reflux
Bo Li, Yonghui Pang, Xuejiao Wang, Xudong Tang
4TMR Theory and Hypothesis. 2019, 2 (2): 189-194.   https://doi.org/10.12032/TMRTH201902005
Abstract ( 51 )     PDF (350KB) ( 17 )  
Professor Xudong Tang believes that definite diagnosis is the key to gastroesophageal reflux disease
treatment, and the treatment of refluxesophagitis should be combined with PH monitoring and
clinical symptoms differentiation. Generally, according to the degree of acid regurgitation, it can
be divided into different traditional Chinese medical syndromes: the liver-stomach depressionheat
syndrome differentiation is the main type of acid regurgitation, while the liver-qi stagnation is
the main type of acid regurgitation. In addition, attention should be paid to the step-down therapy
of combination of traditional Chinese and Western medicine in the process of discontinuation.
The lower efficacy of Western medicine should be used successively, together with traditional
Chinese medicine Decoction, which can often achieve the effect of stopping recurrence. In addition,
the traditional Chinese medicine prescription imitates Jianhua Dong's well-known old Chinese
medicine thought, believing that the pathogenesis of gastroesophageal reflux disease is mainly Qi
stagnation, the location of the disease is in the stomach, involving the liver and spleen. On the basis
of Dr Dong Ganwei Baihe Decoction, the experience of treating gastroesophageal reflux disease
with Lianzhu Liuyi Pill combined with Huagan Decoction was summarized

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