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Traditional Medicine Research  2016, Vol. 1 Issue (1): 52-57    DOI: 10.12032/TMR201601007
Orginal Article     
Complete response of hepatocellular carcinoma treated with traditional Chinese medicine treatment: A case report
Cui-HongZhu1, Hao Jian1, Yang Xue1, Wang Xiao-Dong1, Xiong-ZhiWu1,*
1 Zhong-Shan-Men Inpatient Department, National Clinical Research Center for Cancer
Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300171, China
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We reported a detailed clinical course of complete response of hepatocellular carcinoma(HCC) with traditional Chinese medicine(TCM) treatment in the present study. In June 2011, a 47-year-old man was admitted to our hospital for multiple mass lesions in liver. Abdominal contrast-enhanced CT revealed multiple low density nodules with heterogeneous enhancementin his right lobe of the liver and the largest nodule diameter was about 5 cm. The clinical diagnosis was hepatocellular carcinoma (diffuse-type). Resection was not performed considering the patient’s poor physical condition. He received THM therapy as an alternative. One months later, CT showed that the majority lesions of the right liver lobe shrank. In November 2014, CT showed that the liver lesions completely disappeared and had no evidence of tumor recurrence. Our case provides additional evidence to show that TCM treatment is effective for patients with HCC, and it can achieve complete remission, long disease-free survival and provide patients with good quality of life.



Key wordsHepatocellular carcinoma      Complete response      traditional Chinese medicine     
Published: 28 December 2016
Corresponding Authors: Xiong-ZhiWu   
About author:

Executive Editor: Cui-Hong Zhu

English Editor: Lin Li, Li-Yun-Cui, Ya-Song Wang, Xiao-Hua Zhang, Xiao-Dong Wang, Hong-Xu Zhu, Zhen-Yan Liu, Yi-Cheng Shi

Cite this article:

Cui-HongZhu, Hao Jian, Yang Xue, Wang Xiao-Dong, Xiong-ZhiWu. Complete response of hepatocellular carcinoma treated with traditional Chinese medicine treatment: A case report. Traditional Medicine Research, 2016, 1(1): 52-57. doi: 10.12032/TMR201601007

URL:

https://www.tmrjournals.com/tmr/EN/10.12032/TMR201601007     OR     https://www.tmrjournals.com/tmr/EN/Y2016/V1/I1/52

Figure 1 Arterial phase scans of contrast enhanced multiphase computed tomogram of abdomen. A:Abdominal CT scan showed multiplelow density nodules with heterogeneous enhancement in his right lobe of the liver and the largest nodule diameter was about 5 cm. B:Abnormal strengthening signals inright lobe of the liver mostly disappeared in 1 mo-follow-up CT scans.C:Ony multiple nodular sclerosis were noted in 8 mo-follow-up CT scans. D: There was no arterial enhancing viable portion in his right lobe of the liver in abdominal CT scans 37 months after treatment of TCM.
Variable Characteristics
Age, y 43
Gender Male
Nationality Mongol
Child-Pugh score B
AFP 10.5
Primary tumor size (cm) 5
Number oftumors Multiple
Extrahepatic metastases No
Presence of portal vein tumor thrombus No
Surgical resection No
Time of TCM treatment (month) 37months
Survival status Survival(CR)
Table1 Patient baseline characteristics.
2011.6.23 Codonopsis pilosula(党参)30g Nidus Vespae(蜂房)10g Lilac Pink Herb(瞿麦)30g Prepared Jackinthepulpit Tuber(制天南星)30g Gekko japonicus Dumeril et Bibron(天龙)5g Turtle processed with vinegar(醋鳖甲)10g Chinese thorowax root(柴胡)24g Liquorice root(甘草)3g Adlay(薏苡仁)60g Baical skullcap root(黄芩)10g Nightshade(龙葵)15g India madder root(茜草)30g Mealy fangji root(防己)30g Campsis grandiflora(凌霄花)6g Endothelium corneum gigeriae galli(鸡内金)10g Paniculate bolbostemm(土贝母)6g Phytolacca processed with vinegar(醋商陆)9g Processed pinellia tuber(法半夏)9g Radix Notoginseng(三七)2g
2011.7.22 add Bile arisaema(胆南星)30g Root of Valvate Actinidia(猫人参)30g Turmeric root tuber (郁金)10g
subtract Prepared jackinthepulpit tuber制天南星30g
2011.8.26 add Herba Hedyotis(白花蛇舌草)30g Seaweed(海藻)30g
subtract Nidus Vespae(蜂房)10g Liquorice root(甘草)3g Adlay(薏苡仁)60g Baical skullcap root(黄芩)10g
2012.6.5 Radix Notoginseng(三七)2g Phytolacca processed with vinegar(醋商陆)9g Gekko japonicus Dumeril et Bibron(天龙)6g Chinese thorowax root(柴胡)24g Radix Codonopsis(党参)30g Trumpetcreeper flower(凌霄花)6g Lilac pink herb瞿麦30g Turtle processed with vinegar(醋鳖甲)10g Nightshade(龙葵)15g endothelium corneum gigeriae galli鸡内金10g Mealy fangji root(防己)30g Paniculate bolbostemm(土贝母)6g Processed pinellia tuber(法半夏)9g Root of Valvate Actinidi(猫人参)30g European verbena herb(马鞭草)30g Pericarpium Arecae(大腹皮)30g Rhizoma Curcumae Longae(姜黄)6g Baical skullcap root(黄芩)10g cassia twig(桂枝)12g White peony root(白芍)10g Dried ginger(干姜)3g Radix Trichosanthis(天花粉)10g Oyster shell(牡蛎)20g Roasted licorice(炙甘草)3g
2012.7.31 add Nidus Vespae by stir-frying(炒蜂房)6g Radix Actinidiae Chinensis(藤梨根)30g Akebia fruit(预知子)3g
subtract Radix Notoginseng(三七)2g Lilac pink herb(瞿麦)30g Gekko japonicus Dumeril et Bibron(天龙)6g Rhizoma Curcumae Longae(姜黄)6g Root of Valvate Actinidia(猫人参)30g
2012.11.13 add Radix Notoginseng(三七)2g Lilac pink herb(瞿麦)30g Gekko japonicus Dumeril et Bibron(天龙)6g Rhizoma Curcumae Longae(姜黄)6g Root of Valvate Actinidia(猫人参)30g
subtract Processed pinellia tuber(法半夏)6g Nidus Vespae by stir-frying炒蜂房6g Radix Actinidiae chinensis(藤梨根)30g Akebia fruit(预知子)3g
2013.11.14 add Fresh bone fossil of big mammals生龙骨15g Coix seed(薏苡仁)10g
subtract Rhizoma Atractylodis Macrocephalae(白术)20g oyster shell(牡蛎)15g
Table2 Prescriptions of traditional Chinese medicine treatment.
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