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05 January 2016, Volume 1 Issue 1    Next Issue
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Orginal Article
TMR:A new star for the research of traditional medicine
Traditional Medicine Research. 2016, 1 (1): 1-2.   https://doi.org/10.12032/TMR201601001
Abstract ( 303 )   HTML ( 17 )     PDF (123KB) ( 126 )  
Effects and safety of acupuncture for DFUs: a systematic review and meta-analysis
Yi Li-Juan, Tian Xu, Shuai Ting, Zeng Zi, Ma Li, Song Guo-Min
Traditional Medicine Research. 2016, 1 (1): 2-10.   https://doi.org/10.12032/TMR201601002
Abstract ( 577 )   HTML ( 20 )     PDF (703KB) ( 191 )  

Objective:To systematically evaluate the effect and safety of acupuncture for the treatment of diabetic foot ulcers(DFUs).Methods:Six databases, including Pubmed, Web of Science, EMbase, the Cochrane Library, the Chinese Biomedical Literature Database (CBM), and the China National Knowledge Infrastructure (CNKI), were electronic searched for randomized controlled trials (RCTs). Retrieval periods from each database were stopped until30 October, 2014. Cochrane risk of bias assessment tool was used to assess the methodological quality of included studies. Results:A total of 8 trials involving 481 participants met the inclusion criteria. The results of meta and descriptive analysis suggested that acupuncture effectively improved total effective rate of DFUs,shortened ulcer healing time , and improved the blood flow volume,but acupuncture did not ameliorate vessel diameter and peak velocity. No serious adverse events were identified in acupuncture group.Conclusions:Acupuncture is more effective in shortening overall treatment time. Acupuncturehas advantages over the control group in curative effect.

The effect of acupuncture plus drug versus drug alone on patients with mild cognitive impairment: a systematic review
Shuai Ting, Zhang Hui, Yi Li-Juan, Tian Xu, Zeng Zi, Wang Yan, Song Guo-Min
Traditional Medicine Research. 2016, 1 (1): 11-20.   https://doi.org/10.12032/TMR201601003
Abstract ( 406 )   HTML ( 5 )     PDF (1188KB) ( 270 )  

Objective:The aim of this systematic review is to evaluate the effect of acupuncture plus drug versus drug alone on patients with MCI.Methods:A computerized search of the databaseswas performed from inception through February 2015. The screening of literature, the extraction of data and the assessment of methodology were independently undertaken by two reviewers. Then, a meta-analysis was performed by Review manager 5.3 version.Results:A total of 18 RCTs involving 1095 participants were incorporated into this study. Meta-analysis suggested that acupuncture plus drug for MCI could significantly improve Mini-Mental State Examination scores (MMSE) (MD1.73, 95% CI 1.28 to 2.18, random-effects model, P<0.00001, 12trials). Activities of Daily Livingscores(ADL) could be significantly improved (MD 5.63, 95%CI 4.40 to 6.87, fixed-effect model, P<0.001, 6 trials).Conclusion:With present evidences, acupuncture plus drug is more effective than drug alone for the treatment of MCI.

Review
Experimental research of integrative Chinese medicine in multiple sclerosis
Ke-Ying Zhu, Zheng Kang, Yan Chen, Gen-Cheng Wu, Jun Wang
Traditional Medicine Research. 2016, 1 (1): 21-31.   https://doi.org/10.12032/TMR201601004
Abstract ( 307 )     PDF (627KB) ( 256 )  
Multiple sclerosis (MS) is a severe neurodegenerative disease which brings overwhelming sufferings to patients and their families with no radical cure heretofore. Thus, studies of different medicine field and diverse treating methods aiming at the cure for MS should be promoted. Traditional Chinese medicine (TCM) as one of the most important complementary and alternative medicine (CAM), has long been applied to treat MS in China and other nervous system diseases worldwide. Our review aims to summarize the findings of Chinese herbal medicine and acupuncture in the prevention and treatment on animal model of MS, mainly based on experimental autoimmune encephalomyelitis (EAE) model. In this review, experimental research advances of Traditional Chinese medicine in the studies of MS are involved, including Chinese herb decoctions, herb extracts like huperzine A, Eriocalyxin B, Curcumin and also, acupuncture. All of this researches hew out new thoughts towards the treatment of MS and concomitantly, the understanding of the effective mechanism of TCM on MS.
Keywords: Multiple sclerosis, Traditional Chinese medicine, Complementary and alternative medicine, Experimental autoimmune encephalomyelitis, Acupuncture
Massage for migraine: A meta-analysis
Xiao-Yi Tang, Wen-Ru Shang, Zhi-Wen Weng, Rui-Jin Qiu, Jin-Hui Tian, Yan-Gang Liu, Gui-Hua Tian
Traditional Medicine Research. 2016, 1 (1): 32-42.   https://doi.org/10.12032/TMR201601005
Abstract ( 419 )   HTML ( 7 )     PDF (653KB) ( 271 )  

Objective:This systematic review examined whether massage interventions provided any measurable benefit in migraine disorders. Methods:Randomized controlled trials (RCTs) were searched for in Cochrane Library, PubMed, Web of Science, China Knowledge Resource Integrated Database (CNKI), and WanFang Data from inception to October 2015. Two researchers independently selected literatures according to the inclusion criteria, and used the risk of bias assessment tool in Reviewer Handbook 5.1.0 for quality evaluation. Meta-analyses were performed with RevMan 5.3 software. GRAED pro GDT was used to evaluate the quality of evidence. Results:In summary, 18 RCTs with2025 patients and 1947 cases were included in meta-analyses. Analysis results showed that 1) compared with conventional drug therapies, massage therapies significantly improved the effective rate with statistically significant difference (RR=1.25, 95%CI (1.19, 1.32), P<0.00001); 2) the difference between massage and acupuncture was not statistically significant (RR=0.94, 95%CI (0.77, 1.16), P>0.05). In addition, compared with acupuncture only, a combined approach of massage and acupuncture significantly improved the effective rate with statistically significant difference (RR=1.11, 95%CI (1.06, 1.17), P<0.0001). Conclusion:As comparable to acupuncture, massage is an effective therapy for migraine, both massage and acupunctureshow clear benefits over conventional drug therapies.

Orginal Article
Similarities and Differencesof Doctor-Patient Co-operated Evidence-Based Medical Record of Treating Digestive System Diseaseswith Integrative Medicine Compared with Traditional Medical Records
BoLi, Wen-HongShao, Yan-DaLi, Ying-PanZhao, Qing-NaLi, Yang Zhao, CaiShang Hong
Traditional Medicine Research. 2016, 1 (1): 43-51.   https://doi.org/10.12032/TMR201601006
Abstract ( 322 )   HTML ( 1 )     PDF (229KB) ( 193 )  

Objective:To establish the model of doctor-patient cooperated record, based on the concepts of narrative evidence-based medicine and related theories on Doctor-Patient Co-operated Evidence-Based Medical Record.Methods:We conducted a literature searchfrom Pubmed, following the principles of narrative evidence-based medicine, and refer to the advice of experts of digestive system and EBM in both traditional Chinese medicine and Western medicine.Result:This research is a useful attempt to discuss the establishment of doctor-patient co-operated evidence-based medical record guided by narrative evidence-based medicine.Conclusion:Doctor-patient co-operated medical record can become a key factor of the curative effect evaluation methodology system of integrated therapy of tradition Chinese medicine and Western medicine on spleen and stomach diseases.

Complete response of hepatocellular carcinoma treated with traditional Chinese medicine treatment: A case report
Cui-HongZhu, Hao Jian, Yang Xue, Wang Xiao-Dong, Xiong-ZhiWu
Traditional Medicine Research. 2016, 1 (1): 52-57.   https://doi.org/10.12032/TMR201601007
Abstract ( 436 )   HTML ( 6 )     PDF (317KB) ( 215 )  

We reported a detailed clinical course of complete response of hepatocellular carcinoma(HCC) with traditional Chinese medicine(TCM) treatment in the present study. In June 2011, a 47-year-old man was admitted to our hospital for multiple mass lesions in liver. Abdominal contrast-enhanced CT revealed multiple low density nodules with heterogeneous enhancementin his right lobe of the liver and the largest nodule diameter was about 5 cm. The clinical diagnosis was hepatocellular carcinoma (diffuse-type). Resection was not performed considering the patient’s poor physical condition. He received THM therapy as an alternative. One months later, CT showed that the majority lesions of the right liver lobe shrank. In November 2014, CT showed that the liver lesions completely disappeared and had no evidence of tumor recurrence. Our case provides additional evidence to show that TCM treatment is effective for patients with HCC, and it can achieve complete remission, long disease-free survival and provide patients with good quality of life.

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